ID   D6A0H6_STRV1            Unreviewed;       254 AA.
AC   D6A0H6;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=IclR-family transcriptional regulator {ECO:0000313|EMBL:EFE67397.2};
GN   ORFNames=SSFG_02646 {ECO:0000313|EMBL:EFE67397.2};
OS   Streptomyces viridosporus (strain ATCC 14672 / DSM 40746 / JCM 4963 / KCTC
OS   9882 / NRRL B-12104 / FH 1290) (Streptomyces ghanaensis).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=566461 {ECO:0000313|EMBL:EFE67397.2, ECO:0000313|Proteomes:UP000003824};
RN   [1] {ECO:0000313|Proteomes:UP000003824}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14672 / DSM 40746 / JCM 4963 / KCTC 9882 / NRRL B-12104 /
RC   FH 1290 {ECO:0000313|Proteomes:UP000003824};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Ward D., Young S., Kodira C.D., Zeng Q., Koehrsen M.,
RA   Godfrey P., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland B.L.C., Ilzarbe M.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces ghanaensis ATCC 14672.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS999641; EFE67397.2; -; Genomic_DNA.
DR   RefSeq; WP_004983963.1; NZ_DS999641.1.
DR   AlphaFoldDB; D6A0H6; -.
DR   eggNOG; COG1414; Bacteria.
DR   Proteomes; UP000003824; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          2..61
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          62..245
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
SQ   SEQUENCE   254 AA;  28038 MW;  6E7A8F0B7457A3B1 CRC64;
     MSQTVDRALS ILPLLAEGPA DLGQVADRLG VHKSTALRLL RTLHEHGLVY RQSDQRYRLG
     ARLFALAQEA MENLDVREIA HPHLVRLNES CGHTVHLAVY EENEVLYIDK VESRYPVRMY
     SRIGKPVAIT VAAVAKLLLA DLPEHERRAL AEKLDYPMYT SRSTPHPAAF LRELEKVREQ
     GWATDLGGHE ESINCVAAPV RGADGRVVAA MSVSAPNVVV TADELLTLLP LVRRTADAIS
     SEYSGRTPVK DTPA
//