ID   D6A390_STRV1            Unreviewed;       605 AA.
AC   D6A390;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:EFE67592.2};
GN   ORFNames=SSFG_02839 {ECO:0000313|EMBL:EFE67592.2};
OS   Streptomyces viridosporus (strain ATCC 14672 / DSM 40746 / JCM 4963 / KCTC
OS   9882 / NRRL B-12104 / FH 1290) (Streptomyces ghanaensis).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=566461 {ECO:0000313|EMBL:EFE67592.2, ECO:0000313|Proteomes:UP000003824};
RN   [1] {ECO:0000313|Proteomes:UP000003824}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14672 / DSM 40746 / JCM 4963 / KCTC 9882 / NRRL B-12104 /
RC   FH 1290 {ECO:0000313|Proteomes:UP000003824};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Ward D., Young S., Kodira C.D., Zeng Q., Koehrsen M.,
RA   Godfrey P., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland B.L.C., Ilzarbe M.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces ghanaensis ATCC 14672.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS999641; EFE67592.2; -; Genomic_DNA.
DR   RefSeq; WP_004984333.1; NZ_DS999641.1.
DR   AlphaFoldDB; D6A390; -.
DR   eggNOG; COG2303; Bacteria.
DR   Proteomes; UP000003824; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          209..298
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00732"
FT   DOMAIN          493..550
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
SQ   SEQUENCE   605 AA;  65010 MW;  4D89EF009B23C9B8 CRC64;
     MSQENPVHEP DDDAAYDYDV IVVGSGFGGS VSALRLTEKG YRVGVLEAGR RFTRESLPKN
     SWDLKNYLWA PGLGMYGIQR IHLLGNVMVL AGAGVGGGSL NYANTLYVPP KPFFDDPQWR
     DITDWQEELK PYYDQARRML GVRLNPTTTP SDVHLRAAAE RMGVGDTFHM APVGVFFGDG
     EDADGKVRAE PGQEVPDPYF GGAGPSRRAC AECGECMTGC RHGAKNTLNE NYLHLAEKAG
     AVVHPMTTAV SVTEDPRGGY AVVTLPTDDR RKGKDRTFRA RRVVLAAGTY GTQTLLHRMK
     AAGRLPHLSD RLGELTRTNS EALVGAQTDD RRYRRATGAP KVDFTRGVAI TSSIHPDENT
     HIEPVRYGRG SNSMGSLSIL QVPYAGSGSG AARVLGWLGN AARHPWLMLR SLSNRRWSER
     TIIGLVMQSL DNSLTTYLKP SGIGRGLLTA RQGHGAPNPK QIKAATDGAS ALAAEINGFA
     GSNIGELTGM PLTAHFLGGC PIGASRETGV IDPYHRLYGH PGISVVDGAA VSANLGVNPS
     LTITAQAERA MSYWPNKGEA DPRPEQGAAY RRLQPVEPKS PAVPADAFGA LKLPFLGMPT
     VPPKE
//