ID   D6D7V1_9BACE            Unreviewed;       654 AA.
AC   D6D7V1;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   24-JAN-2024, entry version 58.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=BXY_09310 {ECO:0000313|EMBL:CBK66096.1};
OS   Bacteroides xylanisolvens XB1A.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=657309 {ECO:0000313|EMBL:CBK66096.1, ECO:0000313|Proteomes:UP000008795};
RN   [1] {ECO:0000313|EMBL:CBK66096.1, ECO:0000313|Proteomes:UP000008795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XB1A {ECO:0000313|EMBL:CBK66096.1,
RC   ECO:0000313|Proteomes:UP000008795};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Bernalier A.;
RT   "The genome sequence of Bacteriodes xylanisolvens XB1A.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBK66096.1, ECO:0000313|Proteomes:UP000008795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XB1A {ECO:0000313|EMBL:CBK66096.1,
RC   ECO:0000313|Proteomes:UP000008795};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; FP929033; CBK66096.1; -; Genomic_DNA.
DR   AlphaFoldDB; D6D7V1; -.
DR   CAZy; GH20; Glycoside Hydrolase Family 20.
DR   KEGG; bxy:BXY_09310; -.
DR   PATRIC; fig|657309.4.peg.4504; -.
DR   eggNOG; COG3525; Bacteria.
DR   HOGENOM; CLU_007082_5_0_10; -.
DR   Proteomes; UP000008795; Chromosome.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000313|EMBL:CBK66096.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CBK66096.1}.
FT   DOMAIN          1..115
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          119..461
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   DOMAIN          525..645
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|Pfam:PF00754"
FT   ACT_SITE        292
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   654 AA;  73734 MW;  0800C20FEB6CD07D CRC64;
     MEQGTGCFLL SENTKLYINL QGLEAQLLEN CLQALPVHLK KGKKKDTQNI LSLLITEKNH
     QLPSPESYTL SVTPQQILIR ATSGAGLFYG LQTLLQLAQP SGAGSYSIAS VEIEDTPRFA
     YRGLMLDVSR HFSTKEFIKK QIDALAYYKI NRLHLHLTDA AGWRLEIKKY PLLTEFAAWR
     TDPTWKQWWN GGRKYVRFDA PGAYGGYYTQ DDIREILEYA RQHYITVIPE IEMPSHSEEV
     LAAYPQLSCS GEPYKNSDFC VGNEETFTFL ENVLTEVMEL FPSEYIHIGG DEAGKSAWKT
     CPKCQKRMTD EHLANVDELQ SYLIHRIEKF LNNHGRHLLG WDEILQGGIA PNATVMSWRG
     EEGGIAAVTS GHRAIMTPGA YCYLDSYQDA PYSQPEAIGG YLPLKKVYSY NPVPASLTAE
     QAKLVYGVQG NLWVEYIPTP EHVEYMIYPR ILALAETAWS APERKSWPDF HTRALSAVAD
     LQAKGYHPFD LKKEIGSRPE SLQSVSHLAL GKKVIYNSPY SSHYPAQGNT ALTDGIRGDW
     TYGDGSWQGF ISDNRLDVTI DMEKETSIHS VTAAFMQVVG AEVFLPETVV ISISDDGTHF
     TELRKQHFEV SKETPIRFTD ISWQGEAKGR YVRYQAQAGS EFGGWIFTDE IIVK
//