ID D6E8J1_9ACTN Unreviewed; 932 AA.
AC D6E8J1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Cell elongation-specific peptidoglycan biosynthesis regulator RodA/cell elongation-specific peptidoglycan D,D-transpeptidase {ECO:0000313|EMBL:CBL04038.1};
GN ORFNames=GPA_14330 {ECO:0000313|EMBL:CBL04038.1};
OS Gordonibacter pamelaeae 7-10-1-b.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Gordonibacter.
OX NCBI_TaxID=657308 {ECO:0000313|EMBL:CBL04038.1, ECO:0000313|Proteomes:UP000008805};
RN [1] {ECO:0000313|EMBL:CBL04038.1, ECO:0000313|Proteomes:UP000008805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7-10-1-b {ECO:0000313|Proteomes:UP000008805};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Timmis K., Oxley A., Wurdemann D.;
RT "The genome sequence of Gordonibacter pamelaeae 7-10-1-bT.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL04038.1, ECO:0000313|Proteomes:UP000008805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7-10-1-b {ECO:0000313|Proteomes:UP000008805};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; FP929047; CBL04038.1; -; Genomic_DNA.
DR RefSeq; WP_015539388.1; NC_021021.1.
DR AlphaFoldDB; D6E8J1; -.
DR KEGG; gpa:GPA_14330; -.
DR PATRIC; fig|657308.3.peg.1019; -.
DR HOGENOM; CLU_012814_1_0_11; -.
DR BioCyc; GPAM657308:GPA_RS06675-MONOMER; -.
DR Proteomes; UP000008805; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001182; FtsW/RodA.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF01098; FTSW_RODA_SPOVE; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008805};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 609..926
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 932 AA; 98371 MW; 3E7CB0D9B4AEBB82 CRC64;
MTRRNLELVL LCVAAPIVVL LFAMLAINQG QSLNATTLGV PIGIFVAFVI AHLAVRKFAP
KADPAILPIS FALSGIGIAF ITRLAPYADK SSIAINQVMW LFLGVACMVL VLVLFRNLDK
VANYKYTLMI VGFALLLSPL LPVIGQEIYG SRIWIGIPGV FSFQPGEIAK IAIVLFLAGY
LAQNREMLSV FTWRAGPFNL PDIRTLLPLL LMWLVALLIV VFEKDLGSAL VFFFVFLIML
YVATGKKFYL VVGLGLIAVG GVGAYLAFGH VQTRVDIWLD PFADAQNTGY QLVQSLYSIA
DGDLFGVGLG RGLAGGGNGL PQIPVAESDF IFTVIAEEIG LLGAAGVLLL FLCFAIRGFV
TAARAKSDVS SFVAVGLTSI VVLQAFIIVG GITRLIPLTG ITLPFISQGG SSLLASFIIV
GFLLRCGDEG TGVGEEMASA TTSLHANSVL GRVSLGKRLT HAMIILSTLF ALLVANLTLI
MVVQASYYQN MPGNNHTMAK ESRTERGTIS TYDGVILAQS VQQEDGTYER VYPAGNLATH
VVGYASTQFG TSGIEAAEND TLKGQQNYAS WTDVLNSLAG VGGVGNDVTL TLNSKIQQAA
QDALSGYAGA CVVMDPETGA VLGMASSPTY DAADFAAEIE KANANPDGES TLLNRAIQTL
YAPGSTFKIV TLATALEDGV ASEDTVFSSP GTMDIGNAPV TNFNKNSYGD ITLARATELS
SNTVFGQLGV EMGAEKLVDG ADKFGFNRKI DFTLNTATSL MAEPDEMTKW ELAWSAAGEP
VNPQNHPSPA GPQATVLEMA LVGCAIANDG AIMNPYLVEG VYNANGERSF TATPNKFLQA
VSKETASRVK DVLKGVVTDG TGTAAALPGV EVAGKTGTAE KENGNDSWFV GMAPADNPRV
VVAINLELAD EGMGTERAQN VLRTALQVQG LL
//
