ID D6K900_9ACTN Unreviewed; 515 AA.
AC D6K900;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Secreted hydrolase {ECO:0000313|EMBL:EFF92212.2};
GN ORFNames=SSTG_02531 {ECO:0000313|EMBL:EFF92212.2};
OS Streptomyces sp. e14.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=645465 {ECO:0000313|EMBL:EFF92212.2, ECO:0000313|Proteomes:UP000004704};
RN [1] {ECO:0000313|EMBL:EFF92212.2, ECO:0000313|Proteomes:UP000004704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=e14 {ECO:0000313|Proteomes:UP000004704};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain e14.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S33 family.
CC {ECO:0000256|ARBA:ARBA00010088}.
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DR EMBL; GG753626; EFF92212.2; -; Genomic_DNA.
DR AlphaFoldDB; D6K900; -.
DR STRING; 645465.SSTG_02531; -.
DR ESTHER; 9actn-d6k900; Tiancimycin-TnmK-Tripeptidase-HIP.
DR eggNOG; COG0596; Bacteria.
DR Proteomes; UP000004704; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR013595; Pept_S33_TAP-like_C.
DR PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF08386; Abhydrolase_4; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFF92212.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000004704};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..49
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 50..515
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003085709"
FT DOMAIN 118..280
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT DOMAIN 415..510
FT /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08386"
SQ SEQUENCE 515 AA; 56239 MW; BF14EAAD77D20BB6 CRC64;
MRLRRPPTPR HPSPTRTSIT VRTTRRASLT AVGAVVASLM TLTPTTAVAA SGAAAPDPLR
RYTQQKLDWR PCDAKTAPAA FQCATLKVPL DYGDPGGEQL TIAVDRLRAG SAEDRRGVLL
FNPGGPGAPG LDLPVALEAF LPREVKRRYD LVGFDPRGIG QSSPLSCGLS SDELNFDRPY
HAETFAKDVR WARTVAAKCE AAAGRKLRHI TTRDTARDMD VLRAALGERK ISYYGGSYGT
YLGAVYLQMF PRRADRFVLD SAVDPVRYGR GTFQEMAQGT EPAFVRWSRW TARRHTTYRL
GTTPAEVRAT FWDIVARADR APVVTDGGTL TGDDIRSARD VFFQERKAAD WVAGLKKAAE
AAEPAAPAPD PELPPENTIA GLWAVMCGDT AAAWPRDPEQ YRRDAVRDKA RYPLYGDFAS
TVKPCAFWKP GSEAATKVDN DAEALILQNE WDPQTPLSAA RSMHRALHGS RMVTVAGGEG
HGVYGARSCA DEVADDYLIT GRLPAEDRTC PIVRP
//
