ID D6RCK0_MOUSE Unreviewed; 198 AA.
AC D6RCK0;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Mitochondrial tRNA translation optimization 1 {ECO:0000313|Ensembl:ENSMUSP00000121424.2};
GN Name=Mto1 {ECO:0000313|Ensembl:ENSMUSP00000121424.2,
GN ECO:0000313|MGI:MGI:1915541};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121424.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000121424.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121424.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000121424.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121424.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR AlphaFoldDB; D6RCK0; -.
DR SMR; D6RCK0; -.
DR MaxQB; D6RCK0; -.
DR PeptideAtlas; D6RCK0; -.
DR ProteomicsDB; 359692; -.
DR Antibodypedia; 31347; 117 antibodies from 24 providers.
DR Ensembl; ENSMUST00000148238.2; ENSMUSP00000121424.2; ENSMUSG00000032342.14.
DR UCSC; uc009qul.2; mouse.
DR AGR; MGI:1915541; -.
DR MGI; MGI:1915541; Mto1.
DR VEuPathDB; HostDB:ENSMUSG00000032342; -.
DR GeneTree; ENSGT00390000011297; -.
DR HOGENOM; CLU_121987_0_0_1; -.
DR ChiTaRS; Mto1; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000032342; Expressed in proximal tubule and 252 other cell types or tissues.
DR ExpressionAtlas; D6RCK0; baseline and differential.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR002218; MnmG-rel.
DR InterPro; IPR040131; MnmG_N.
DR PANTHER; PTHR11806; GLUCOSE INHIBITED DIVISION PROTEIN A; 1.
DR PANTHER; PTHR11806:SF0; PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL; 1.
DR Pfam; PF01134; GIDA; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 1: Evidence at protein level;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Proteomics identification {ECO:0007829|EPD:D6RCK0,
KW ECO:0007829|MaxQB:D6RCK0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 37..178
FT /note="MnmG N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01134"
SQ SEQUENCE 198 AA; 21280 MW; 350EC740FEEB4D55 CRC64;
MFLLRGRGHW AAASLGRRLP LRRLRSDSAA PCTPHFDVVV IGGGHAGTEA AAAAARCGSR
TLLLTHRVDT IGQMSCNPSF GGIGKGHLMR EVDALDGLCS RICDQSGIHY KVLNRRKGPA
VWGLRAQIDR KLYKQNMQKE ILSTPLLTVQ KGAVEDLVLA EPEPGYPGKS RVRGVVLAGR
PTAMLLDSHQ PPSGCDCP
//
