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Database: UniProt
Entry: D6RCY9_MOUSE
LinkDB: D6RCY9_MOUSE
Original site: D6RCY9_MOUSE 
ID   D6RCY9_MOUSE            Unreviewed;       370 AA.
AC   D6RCY9;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   18-JUL-2018, entry version 60.
DE   SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSMUSP00000119086};
GN   Name=Sh2b3 {ECO:0000313|Ensembl:ENSMUSP00000119086,
GN   ECO:0000313|MGI:MGI:893598};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119086, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000119086, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119086,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000213|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and
RT   expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000119086}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119086};
RG   Ensembl;
RL   Submitted (MAY-2011) to UniProtKB.
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DR   EMBL; AC113302; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; D6RCY9; -.
DR   MaxQB; D6RCY9; -.
DR   PRIDE; D6RCY9; -.
DR   Ensembl; ENSMUST00000136960; ENSMUSP00000119086; ENSMUSG00000042594.
DR   MGI; MGI:893598; Sh2b3.
DR   eggNOG; ENOG410IFCS; Eukaryota.
DR   eggNOG; ENOG410YMBM; LUCA.
DR   GeneTree; ENSGT00530000063355; -.
DR   ChiTaRS; Sh2b3; mouse.
DR   Proteomes; UP000000589; Chromosome 5.
DR   Bgee; ENSMUSG00000042594; -.
DR   ExpressionAtlas; D6RCY9; baseline and differential.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0030097; P:hemopoiesis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030522; SH2B3.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF1; PTHR10872:SF1; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Proteomics identification {ECO:0000213|MaxQB:D6RCY9,
KW   ECO:0000213|PeptideAtlas:D6RCY9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN       23     76       Phe_ZIP. {ECO:0000259|Pfam:PF08916}.
FT   DOMAIN      190    276       PH. {ECO:0000259|Pfam:PF00169}.
SQ   SEQUENCE   370 AA;  40657 MW;  F1D647B85D150D1E CRC64;
     MNEPTVQPSR TSSAPASPAS PRGWSDFCEQ HAAAAARELA RQYWLFARAH PQPPRADLVS
     LQFAELFQRH FCREVRESLA GPPGHDYRAT APPRPALPKA RSSEDLGPRP ACALQHLRRG
     LRQLFRRRSA GELPGATSDT NDIDTTAASR PGPARKLLPW GLREPPTEAL KEVVLRYSLA
     DEAAMDSGAR WQRGRLVLRS PGPGHSHFLQ LFDPPKSSKP KLQEACSSIR EVRPCTRLEM
     PDNLYTFVLK VQDQTDIIFE VGDEQQLNSW LAELRASTGL GLEHPDTELP LSLAAEPGPA
     RSPRGSTDSL DQGMCQVLGL WVSLDMWPPC GSPPPSFRQV LHLGCCWTQP ARKQITSYPA
     TPGSTAPSPG
//
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