ID D6RLC7_COPC7 Unreviewed; 707 AA.
AC D6RLC7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN ORFNames=CC1G_14181 {ECO:0000313|EMBL:EFI28154.1};
OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS (Inky cap fungus) (Hormographiella aspergillata).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinopsis.
OX NCBI_TaxID=240176 {ECO:0000313|EMBL:EFI28154.1, ECO:0000313|Proteomes:UP000001861};
RN [1] {ECO:0000313|EMBL:EFI28154.1, ECO:0000313|Proteomes:UP000001861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003
RC {ECO:0000313|Proteomes:UP000001861};
RX PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J.,
RA Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA Zolan M.E., Pukkila P.J.;
RT "Insights into evolution of multicellular fungi from the assembled
RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFI28154.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACS02000003; EFI28154.1; -; Genomic_DNA.
DR RefSeq; XP_002911648.1; XM_002911602.1.
DR AlphaFoldDB; D6RLC7; -.
DR STRING; 240176.D6RLC7; -.
DR GeneID; 9378323; -.
DR KEGG; cci:CC1G_14181; -.
DR VEuPathDB; FungiDB:CC1G_14181; -.
DR eggNOG; KOG2094; Eukaryota.
DR HOGENOM; CLU_012348_11_2_1; -.
DR InParanoid; D6RLC7; -.
DR OMA; EVYTRQV; -.
DR OrthoDB; 146204at2759; -.
DR Proteomes; UP000001861; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR Gene3D; 1.10.150.810; -; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR HAMAP; MF_01113; DNApol_IV; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR022880; DNApol_IV.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR PIRSF; PIRSF036603; DPol_eta; 3.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001861}.
FT DOMAIN 106..285
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..570
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 79060 MW; 4E2433B312C931BA CRC64;
MTSTGSFPEP SQQSESLTRR LAGPSVTKAG LAHDQTEINR IILEASKGSK FYENEKRKDK
ELTEKINRIL QEKEEAMLGA DMAKLEAMAD QQIMKLESER DLSQFIVHVD MDAFYANVEI
LRDPSLKGKP FAVGRGVMST ASYEARKYGV RSGMAGFIGK KLCPQLIFVP AHFDLYSKTS
AQIMSIFRRY DPTMCPAGVD EAYLNVTAYC KQHGKTVDEV VSEMRKAVFD ETQLTVSAGI
APNKMLAKIC SDKNKPNGQF KLEFEPDSIK AFMHSLSIRK VPGVGRVNER LLDSIGIRTC
GDIYQQRGVI ALMDKRFGLD FLLRVYLGIA SNHVAPHARE ERKSIGAERT FSTLDSNHAD
PKKGSVAIVA KLEEVAEELV EDMKREGWVG KTVTLKYKLD TYQTFTRAKQ FSKWITTKEE
LFNTGKELLL SRFPLRLRLI GLRLTRLKDL RAESKSTGIK RFFEPIKQQQ DRDDAHGPRK
RRRLDPELEE ADDEPPGSQD CMPGFHEHDE RDIELAAFDD DGFEEEGFAI VEDPKSISHT
PKHGPGKDPK RPRPPVSAPA CSPPNHIPPQ TDQAPVRTRA ISIGPISESA GRDGVFLPPP
PEEPPEQDLQ ECPICGRKLR TDNQGLNSHI DFCLSRDAIW DAQTETVQSA GRSGHARANS
EDRDGKRITA HLGKSSHKRP TGAKGKNAST GSRQGVLQWV KQESRKK
//
