ID D6WSE9_TRICA Unreviewed; 1328 AA.
AC D6WSE9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=No mechanoreceptor potential A {ECO:0008006|Google:ProtNLM};
GN Name=AUGUSTUS-3.0.2_09552 {ECO:0000313|EMBL:EFA06632.2};
GN ORFNames=TcasGA2_TC009552 {ECO:0000313|EMBL:EFA06632.2};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:EFA06632.2, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:EFA06632.2, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA06632.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:EFA06632.2, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:EFA06632.2,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ971352; EFA06632.2; -; Genomic_DNA.
DR RefSeq; XP_972761.1; XM_967668.3.
DR STRING; 7070.D6WSE9; -.
DR EnsemblMetazoa; TC009552_001; TC009552_001; TC009552.
DR GeneID; 661513; -.
DR eggNOG; ENOG502QVZW; Eukaryota.
DR HOGENOM; CLU_256595_0_0_1; -.
DR InParanoid; D6WSE9; -.
DR OMA; YPAGDRY; -.
DR OrthoDB; 2872850at2759; -.
DR Proteomes; UP000007266; Linkage group 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01099; PAN_AP_HGF; 4.
DR Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 4.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR47327; FI18240P1-RELATED; 1.
DR PANTHER; PTHR47327:SF9; NO MECHANORECEPTOR POTENTIAL A, ISOFORM A; 1.
DR Pfam; PF00024; PAN_1; 4.
DR SMART; SM00473; PAN_AP; 5.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57414; Hairpin loop containing domain-like; 4.
DR PROSITE; PS50948; PAN; 5.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1190..1215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..140
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 150..234
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 241..325
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 348..427
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 739..832
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 847..1089
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 431..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1274..1306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1328 AA; 150221 MW; 2D3BD4431BA378BF CRC64;
MKSYPYVPSM VHAITVLTVL KMMTKAQTSC GSGSMNGRVM YERLPNIQLQ GFDDDVVRDT
APPFKVLEKC EQLCLTDRAS NNIVRTCTSF DFQPGSRIAT YNGGPEYEES TCYLTAEQAR
PEGIGSLMLV PNSVHFTEVC LTSNRIDRDC PNRLYIFERH PRKKLKLPDA DLKEVMATNR
SECEDKCLNE FSFVCRSATF DPAMRTCTLS RFTRRTHPEL LKDDPNSDYL ENTCLNADRR
CDGLAVFIKE ENKRLGGPFE VDLFTNLTLE ECQSMCVHAE KYFCRSIEYD EMTKVCTLSE
EDSISQKEEI GLASSPTHNF YDFACLDSPR GSEYPDNHAT SHLFSGKKPD TAFQRYRNSR
LGGEHHSEIS GRSLSECLDE CLRQPSFQCK SAEYSERHRI CRLTKFSQKD GMRIIYDADY
DYYENLMLGG DEGQRPGDGY PGGGGDRYRP GGGRYPPVGG GRYPPSRYPP SSGGGDGYDR
PGRPPYDRYP DDRYRPPGGD LYPSGDDRYP PPRPPVDSYP DSGTRYPIGP PGGDRYPGRY
PPGDRDRYPY YPPSSSGGYP SRYPSRYPDK YGDRYGDRYP DKYGDRYPDK YGDRYPDKYD
RYPDKYGDRY GDRYGGLNGR YGESDYYYGG SKYGGGGRYG GDRYWSGPKY GGKYDDRYGN
RHSYYGDERD GGNRWFFRPD RRPGRPVDGG RPIYEPRPPY DGRPYEERPN RRPISPGPDG
PIYDTFGGIG PNRPYSSRCD EGDSFKQVGS RQRLRREFVR KFMNVPSLSQ CQRECTEMRD
FICRSFNYRD VIGREDDRDN CELSDRDSRD LEANSRRFFD NTGNYDFYER SISRQGVDGD
CLDVSQVCNE DGMEFTLRTP EGFYGRIYTY GFYDRCFFRG NGGTVNVLRI SGAQGYPECG
TQRYGDTMTN IVVVQFSDFV QTGRDKRFNL TCLFRGPGEA VVSSGFIGAG SGSPIPIEYL
PAENTLSSKV RLMILYQGRP TTTIAVGDPL TFRLEAQDGY NYITDIFATN VVARDPYSGR
SVQLIDRFGC PVDSFVFPEL DRGRNGDSLE ARFNAFKIPE SNFLVFEATV RTCREGCQPA
YCQTGAGRSE PSFGRKRRSI NETLLLESNN TISAEDDEIT NTTATNDTTV SFLETTKIDT
IDDASEEKES ESPEFVREMI EVFDSREELQ QEARRADPAP ETVCLTPGEY HGLVSAVFAL
IAILLTISLV SGLAYRKYWI VMKKNILADR ASSNISSSYP NTRSSGLSSG ISIFGTGLQK
QFIGFGRSRN FPSLPKDDDI ECPGPAPGGP FEDPSEPIYT DPSLFERSRS LRSIAVSQKR
RKSPGQQI
//
