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Database: UniProt
Entry: D6X5U0_STRE2
LinkDB: D6X5U0_STRE2
Original site: D6X5U0_STRE2 
ID   D6X5U0_STRE2            Unreviewed;       103 AA.
AC   D6X5U0;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   10-APR-2019, entry version 45.
DE   RecName: Full=Urease subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
DE            EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_01954};
DE   AltName: Full=Urea amidohydrolase subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
GN   Name=ureB {ECO:0000256|HAMAP-Rule:MF_01954};
GN   ORFNames=SSDG_07322 {ECO:0000313|EMBL:EFH32060.1};
OS   Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS
OS   914.69 / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=457429 {ECO:0000313|EMBL:EFH32060.1, ECO:0000313|Proteomes:UP000002805};
RN   [1] {ECO:0000313|Proteomes:UP000002805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 /
RC   NRRL 2958 / 5647 {ECO:0000313|Proteomes:UP000002805};
RG   The Broad Institute Genome Sequencing Platform;
RA   Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A.,
RA   Heiman D., Hepburn T., Sykes S., Alvarado L., Kodira C.D.,
RA   Straight P., Clardy J., Hung D., Kolter R., Mekalanos J., Walker S.,
RA   Walsh C.T., Lander E., Galagan J., Nusbaum C., Birren B.;
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EFH32060.1, ECO:0000313|Proteomes:UP000002805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 /
RC   NRRL 2958 / 5647 {ECO:0000313|Proteomes:UP000002805};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Thomson T., Walk T., White J., Yandava C., Straight P.,
RA   Clardy J., Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T.,
RA   Wieland-Brown L.C., Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces pristinaespiralis strain ATCC
RT   25486.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|HAMAP-Rule:MF_01954,
CC         ECO:0000256|SAAS:SAAS01115728};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_01954, ECO:0000256|SAAS:SAAS00779045}.
CC   -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC
CC       (alpha) subunits. Three heterotrimers associate to form the active
CC       enzyme. {ECO:0000256|HAMAP-Rule:MF_01954,
CC       ECO:0000256|SAAS:SAAS00779069}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954}.
CC   -!- SIMILARITY: Belongs to the urease beta subunit family.
CC       {ECO:0000256|HAMAP-Rule:MF_01954, ECO:0000256|SAAS:SAAS00779065}.
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DR   EMBL; CM000950; EFH32060.1; -; Genomic_DNA.
DR   RefSeq; WP_005320344.1; NZ_CM000950.1.
DR   STRING; 457429.ABJI02000718_gene4170; -.
DR   EnsemblBacteria; EFH32060; EFH32060; SSDG_07322.
DR   eggNOG; ENOG4105KI2; Bacteria.
DR   eggNOG; COG0832; LUCA.
DR   BioCyc; GCF_000154945:G1EDT-6137-MONOMER; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000002805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002805};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01954,
KW   ECO:0000256|SAAS:SAAS00779062};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002805}.
SQ   SEQUENCE   103 AA;  10872 MW;  ED980547B31D1B48 CRC64;
     MIPGEILHGE GPILLNQGRE VSRLTVVNAA DRPVQVGSHY HFAEANPGLE FDRTAARGKR
     LNVAAGTAVR FEPGIPVDVE LVPLTGRRIV AGLRGETGGP LDG
//
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