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Database: UniProt
Entry: D6Y5B8_THEBD
LinkDB: D6Y5B8_THEBD
Original site: D6Y5B8_THEBD 
ID   D6Y5B8_THEBD            Unreviewed;       200 AA.
AC   D6Y5B8;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   03-JUL-2019, entry version 47.
DE   RecName: Full=Urease {ECO:0000256|SAAS:SAAS00108089};
DE            EC=3.5.1.5 {ECO:0000256|SAAS:SAAS00108089};
GN   OrderedLocusNames=Tbis_2611 {ECO:0000313|EMBL:ADG89313.1};
OS   Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 /
OS   JCM 10125 / NBRC 14880 / R51).
OC   Bacteria; Actinobacteria; Actinobacteria incertae sedis;
OC   Thermobispora.
OX   NCBI_TaxID=469371 {ECO:0000313|EMBL:ADG89313.1, ECO:0000313|Proteomes:UP000006640};
RN   [1] {ECO:0000313|EMBL:ADG89313.1, ECO:0000313|Proteomes:UP000006640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 /
RC   R51 {ECO:0000313|Proteomes:UP000006640};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Jando M., Schneider S., Klenk H.-P.,
RA   Eisen J.A.;
RT   "The complete genome of Thermobispora bispora DSM 43833.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1.
CC       {ECO:0000256|SAAS:SAAS00108095}.
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DR   EMBL; CP001874; ADG89313.1; -; Genomic_DNA.
DR   RefSeq; WP_013132846.1; NC_014165.1.
DR   STRING; 469371.Tbis_2611; -.
DR   EnsemblBacteria; ADG89313; ADG89313; Tbis_2611.
DR   KEGG; tbi:Tbis_2611; -.
DR   eggNOG; ENOG4108E02; Bacteria.
DR   eggNOG; COG0831; LUCA.
DR   eggNOG; COG0832; LUCA.
DR   HOGENOM; HOG000075053; -.
DR   KO; K14048; -.
DR   OMA; VECVFPD; -.
DR   OrthoDB; 1755809at2; -.
DR   BioCyc; TBIS469371:G1GL8-2603-MONOMER; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000006640; Chromosome.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000006640};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108092};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006640}.
SQ   SEQUENCE   200 AA;  21448 MW;  78DE605130FA20F5 CRC64;
     MHLTPREQER LTIFTLAELA RRRRARGRRL NAPEAIALIC DEILELAWDG ASLEEVVAAA
     RSVLTADDVM EGVPALVPHV QVEALFPNGT ALVAVDQPIG PPAGDDPGAI RTADGEIPIN
     TGRRRIRIAV RNEGDRTVYV SSHFPLSEVN AALVFDREAA AGMRLDIPAG TALAFPPGEE
     RLVDLVATAP QQSAPQESTP
//
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