ID D6Y5K4_THEBD Unreviewed; 372 AA.
AC D6Y5K4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:ADG87350.1};
GN OrderedLocusNames=Tbis_0624 {ECO:0000313|EMBL:ADG87350.1};
OS Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM
OS 10125 / KCTC 9307 / NBRC 14880 / R51).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Thermobispora.
OX NCBI_TaxID=469371 {ECO:0000313|EMBL:ADG87350.1, ECO:0000313|Proteomes:UP000006640};
RN [1] {ECO:0000313|EMBL:ADG87350.1, ECO:0000313|Proteomes:UP000006640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / KCTC 9307 /
RC NBRC 14880 / R51 {ECO:0000313|Proteomes:UP000006640};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Mikhailova N., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Jando M., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Thermobispora bispora DSM 43833.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
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DR EMBL; CP001874; ADG87350.1; -; Genomic_DNA.
DR AlphaFoldDB; D6Y5K4; -.
DR STRING; 469371.Tbis_0624; -.
DR KEGG; tbi:Tbis_0624; -.
DR eggNOG; COG0516; Bacteria.
DR HOGENOM; CLU_064068_0_0_11; -.
DR Proteomes; UP000006640; Chromosome.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006640}.
FT DOMAIN 16..300
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 372 AA; 39830 MW; 34DA933FD1361E62 CRC64;
MSHVEIGRGK SGRRAYALDE IGIVPSRRTR DPEEVSISWQ IDAYRFDIPL VASPMDSVVS
PQTAIEIGRL GGLAVLDLEG LWTRYEDPTP LLEEIASLDD ATATRRLQEI YSAPIQEELI
GRRIEEIRAG GVTTAVRLSP QRTIRYYKAV IDAGVDIFVI RGTTVSAEHV SGRAEPLNLK
QFIYELDVPV IVGGCATYQA ALHLMRTGAA GVLVGFGGGA SHTTRNVLGV AVPMATAISD
VAAARRDYLD ESGGRYVHVI ADGGMGKSGD IAKAIACGAD AVMVGSPLAR AVEAPGRGYH
WGSEAHHPYL PRGKRVKIGT IGTLREILHG PSTIADGSMN LMGALRRTMA TAGYSDLKEF
QRVEVVVAPP QP
//
