ID D6Z036_DESAT Unreviewed; 1472 AA.
AC D6Z036;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:ADH87069.1};
GN OrderedLocusNames=DaAHT2_2404 {ECO:0000313|EMBL:ADH87069.1};
OS Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2).
OC Bacteria; Thermodesulfobacteriota; Desulfobulbia; Desulfobulbales;
OC Desulfobulbaceae; Desulfurivibrio.
OX NCBI_TaxID=589865 {ECO:0000313|EMBL:ADH87069.1, ECO:0000313|Proteomes:UP000001508};
RN [1] {ECO:0000313|Proteomes:UP000001508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19089 / UNIQEM U267 / AHT2
RC {ECO:0000313|Proteomes:UP000001508};
RG US DOE Joint Genome Institute;
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Sorokin D.Y., Muyzer G.,
RA Woyke T.;
RT "Complete sequence of Desulfurivibrio alkaliphilus AHT2.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP001940; ADH87069.1; -; Genomic_DNA.
DR RefSeq; WP_013164581.1; NC_014216.1.
DR STRING; 589865.DaAHT2_2404; -.
DR KEGG; dak:DaAHT2_2404; -.
DR eggNOG; COG1924; Bacteria.
DR eggNOG; COG3580; Bacteria.
DR eggNOG; COG3581; Bacteria.
DR HOGENOM; CLU_002393_2_0_7; -.
DR InParanoid; D6Z036; -.
DR OrthoDB; 9177882at2; -.
DR Proteomes; UP000001508; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 4.
DR Gene3D; 3.40.50.11900; -; 1.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329:SF7; ACTIVATOR OF 2-HYDROXYACYL-COA-HYDRATASE-RELATED; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 2.
DR Pfam; PF09989; DUF2229; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000001508}.
FT DOMAIN 61..254
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 307..564
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 682..896
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
FT REGION 996..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1472 AA; 161839 MW; 1D64C2F9E2452116 CRC64;
MQALGICLGA STISMVGLTR DEGGKITISL QRKRSHEGNP RRVLTEMLAT VEQPPGLKVA
ATGRKFRNHL ALSTIPEPEA VEQACRFVLP PDHSYRTVVS AGGETFMVYR LDDDGRIQHI
QSGNKCASGT GEFLLQQLGR MSLSLEDVEA MGQPAKRYQV SGRCSVFCKS DCTHALNKGI
PKDQVVAGLS RMMAGKILEL LKKMPSDHVL LIGGCAANQS MVHYLREEIA DLAIPDPADA
PPDAMEALGA ALWALEHETR PLPAPEQVFS TRRGSFSHHQ PLTEFRRLVD FKPSTRGQAA
AGDRCILGLD VGSTTTKGVI MRRSDKAIIA ADYLRTDGDP VGASRRVYAS LAQQLGPELS
RSIIIEALGV TGSGRQIAGL HALSEGVINE IIAHATAAVH FDPEVDTIFE IGGQDAKYTY
ITNGVPSDYA MNEACSAGTG SFLEEAAKES LGIGVTEIGE TAYRATSPPN FNDQCAAFIG
SDIKSAAQEG VPLEDIVAGL VYSICMNYTN RVKGNRPVGR KVFIQGGVCY NEAVPAAMAA
LTGKEMVVPP DPGLMGAFGV ALEAERRLEQ GLLEPDRFDL NELAVREVEY GQPFKCGGGK
DCDRGCEISR IIINGKSYPF GGICNRYDNI IHRRKVESSG LDLVVQRERR AFRDAPQATT
PEVDQGFRAP VDAGSPPAEQ KTVGINRSFL INTFFPLFNR FFQELGFKPV LSEKLDPNGV
DKRNAPFCYP VELAHGLFAD LLDKKPDYLF LPHIRAVKVT DDATTSCICP FVQGEPYYLR
ATFPAAEQRP ILTPVFDFSQ GFAANLTVFQ DLARQLGADP RRAEAALKAA IADQESFRND
LKEMGRQALA ELERDPESTA VVLFGRPYNS LVREANKGIP AKFASRGIRI IPIDMLPFED
EPLSADMNMY WAMGRMIMKA ARLVKNHPQL YGTYITNFSC GPDSFLLTYF RDMMGSKPSL
TLELDSHTAD AGLETRIEAF LDIVRYYRQI QTNNADAAEA EQPTQPEQPA PQVDPGPTVS
GPTPQSKEFK PAVTEMRGDE LGIRLADGSW VPMTDPRVKV LVPAMGPFGT SLVAAAFGRR
GIRAEALPPA DEEALKLGRG NSSCKECLPL QTTVGTMLQY LQQKRPEGEI TAYFMATTEG
PCRFGQYHVF SHRTIVRHQI PDAAVMSLTS TNSYGGLGNK FTLAAWRAII IGDLLNEIWS
TIQAGAKDKE AAEAIFWQEQ QKLEQVIASG WATIARQLKA TARELGKIEL HTPHGQIPKL
SLVGEIYVRH DPISLQRLIE RLAAEGFIVR TSQVSEWIKY CDWLVKNRIE GKPDFPWWTR
YWVKRYFDAK IRKLMAPCGL FHYEEKVEVE PLIAAGRRHI APELAGEAIL TVGAALHEIL
HPSCGIISIG PFGCMPTRLA ESILNEKFTS GEKRQVWEAE GHRHIPALLQ KERKLPFLAL
ETDGNAFPQI IEARLEAFAL QAKRVHEDLV NE
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