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Database: UniProt
Entry: D7BHT3_MEISD
LinkDB: D7BHT3_MEISD
Original site: D7BHT3_MEISD 
ID   D7BHT3_MEISD            Unreviewed;       201 AA.
AC   D7BHT3;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   16-JAN-2019, entry version 45.
DE   RecName: Full=Superoxide dismutase {ECO:0000256|RuleBase:RU000414};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000414};
GN   OrderedLocusNames=Mesil_2152 {ECO:0000313|EMBL:ADH64023.1};
OS   Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) (Thermus
OS   silvanus).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae;
OC   Meiothermus.
OX   NCBI_TaxID=526227 {ECO:0000313|EMBL:ADH64023.1, ECO:0000313|Proteomes:UP000001916};
RN   [1] {ECO:0000313|EMBL:ADH64023.1, ECO:0000313|Proteomes:UP000001916}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700542 / DSM 9946 / VI-R2
RC   {ECO:0000313|Proteomes:UP000001916};
RX   PubMed=21304690;
RA   Sikorski J., Tindall B.J., Lowry S., Lucas S., Nolan M., Copeland A.,
RA   Glavina Del Rio T., Tice H., Cheng J.F., Han C., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A.,
RA   Goodwin L., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Lapidus A.;
RT   "Complete genome sequence of Meiothermus silvanus type strain (VI-
RT   R2).";
RL   Stand. Genomic Sci. 3:37-46(2010).
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000414}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC         Evidence={ECO:0000256|RuleBase:RU000414};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000256|RuleBase:RU000414}.
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DR   EMBL; CP002042; ADH64023.1; -; Genomic_DNA.
DR   RefSeq; WP_013158572.1; NC_014212.1.
DR   ProteinModelPortal; D7BHT3; -.
DR   STRING; 526227.Mesil_2152; -.
DR   EnsemblBacteria; ADH64023; ADH64023; Mesil_2152.
DR   KEGG; msv:Mesil_2152; -.
DR   eggNOG; ENOG4105CK4; Bacteria.
DR   eggNOG; COG0605; LUCA.
DR   HOGENOM; HOG000013583; -.
DR   KO; K04564; -.
DR   OMA; KWGSFDK; -.
DR   OrthoDB; 1440645at2; -.
DR   BioCyc; MSIL526227:G1GKK-2161-MONOMER; -.
DR   Proteomes; UP000001916; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001916};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000349-1,
KW   ECO:0000256|RuleBase:RU000414};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000414,
KW   ECO:0000313|EMBL:ADH64023.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001916}.
FT   DOMAIN        5     91       Sod_Fe_N. {ECO:0000259|Pfam:PF00081}.
FT   DOMAIN       99    200       Sod_Fe_C. {ECO:0000259|Pfam:PF02777}.
FT   METAL        29     29       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL        84     84       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       167    167       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
FT   METAL       171    171       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000349-1}.
SQ   SEQUENCE   201 AA;  22981 MW;  C6D427F45ED9F635 CRC64;
     MAYPFKVPER PYAADALEPH IDTKTMEVHY QGHHVAYVNN LNAALEKHPE LHSWELEDLL
     RRINEVPEDI RTAVRNNGGG HHNHTLFWDI LTPGGAKEPT GKLAEAINAT FGSFDEFKKQ
     LTQAGVTRFG SGWAWLVKDK AGKLKIYSTA NQDSPLMEGD TPLLGIDVWE HAYYLKYQNR
     RPEYLAAIWN VINWDKVAER F
//
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