ID D7BM47_ARCHD Unreviewed; 443 AA.
AC D7BM47;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Na+/H+ antiporter NhaC {ECO:0000313|EMBL:ADH91996.1};
GN OrderedLocusNames=Arch_0238 {ECO:0000313|EMBL:ADH91996.1};
OS Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / CCUG 17215 /
OS LMG 16163 / NBRC 15585 / NCTC 8452 / 11018).
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Arcanobacterium.
OX NCBI_TaxID=644284 {ECO:0000313|EMBL:ADH91996.1, ECO:0000313|Proteomes:UP000000376};
RN [1] {ECO:0000313|EMBL:ADH91996.1, ECO:0000313|Proteomes:UP000000376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9345 / DSM 20595 / CCUG 17215 / LMG 16163 / NBRC 15585 /
RC NCTC 8452 / 11018 {ECO:0000313|Proteomes:UP000000376};
RX PubMed=21304742; DOI=10.4056/sigs.1123072;
RA Yasawong M., Teshima H., Lapidus A., Nolan M., Lucas S.,
RA Glavina Del Rio T., Tice H., Cheng J., Bruce D., Detter C., Tapia R.,
RA Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y., Jeffries C., Rohde M., Sikorski J., Pukall R., Goker M.,
RA Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N.,
RA Klenk H.;
RT "Complete genome sequence of Arcanobacterium haemolyticum type strain
RT (11018).";
RL Stand. Genomic Sci. 3:126-135(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002045; ADH91996.1; -; Genomic_DNA.
DR RefSeq; WP_013169494.1; NC_014218.1.
DR AlphaFoldDB; D7BM47; -.
DR STRING; 644284.Arch_0238; -.
DR KEGG; ahe:Arch_0238; -.
DR eggNOG; COG2056; Bacteria.
DR HOGENOM; CLU_037927_0_0_11; -.
DR OrthoDB; 9772446at2; -.
DR Proteomes; UP000000376; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000376};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..86
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 147..437
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 443 AA; 45702 MW; 4FBDA50106AB410C CRC64;
MNAVLIAVVS MLLLALTRVH VVIALFVGAL VGGFTAGLGL DGTMLAFQDG LGAGAKIALS
YGLLGAFAMA VAQSGLPDLL ASWLISRTNK GSTTVVKYGL LGGILMMAVF SQNLIPVHIA
FIPILIPPLI PVFNRLRLDR RVVASIMTFG LVTTYMFLPL GFGSVFLNDI LLGNIKSAGL
DTSGINVMAA MAIPALGMLA GLLIAVGFSY RKPRDYGEDE VVVATTLQPH VSTRNGIVAL
VAVLVTFGTQ LMLGWLGYDA DALLLGSLLG LSVFLITGTL KLRQADVAFT NGMKMMAVIG
FTMISAQGFA SVMNATGDVE SLVEAASALV AGNKALAAVA MLIVGLVVTL GIGSSFSTLP
IITTIYVPLC MSLGFSPLAT VAIIGTAGAL GDAGSPASDS TLGPTSGLNV DGKHDHIRDS
VIPTFLHFNI PLLVAGWIAA MVL
//
