ID D7BNA3_ARCHD Unreviewed; 628 AA.
AC D7BNA3;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:ADH92402.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:ADH92402.1};
GN OrderedLocusNames=Arch_0668 {ECO:0000313|EMBL:ADH92402.1};
OS Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / CCUG 17215 /
OS LMG 16163 / NBRC 15585 / NCTC 8452 / 11018).
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Arcanobacterium.
OX NCBI_TaxID=644284 {ECO:0000313|EMBL:ADH92402.1, ECO:0000313|Proteomes:UP000000376};
RN [1] {ECO:0000313|EMBL:ADH92402.1, ECO:0000313|Proteomes:UP000000376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9345 / DSM 20595 / CCUG 17215 / LMG 16163 / NBRC 15585 /
RC NCTC 8452 / 11018 {ECO:0000313|Proteomes:UP000000376};
RX PubMed=21304742; DOI=10.4056/sigs.1123072;
RA Yasawong M., Teshima H., Lapidus A., Nolan M., Lucas S.,
RA Glavina Del Rio T., Tice H., Cheng J., Bruce D., Detter C., Tapia R.,
RA Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y., Jeffries C., Rohde M., Sikorski J., Pukall R., Goker M.,
RA Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N.,
RA Klenk H.;
RT "Complete genome sequence of Arcanobacterium haemolyticum type strain
RT (11018).";
RL Stand. Genomic Sci. 3:126-135(2010).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP002045; ADH92402.1; -; Genomic_DNA.
DR AlphaFoldDB; D7BNA3; -.
DR STRING; 644284.Arch_0668; -.
DR KEGG; ahe:Arch_0668; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_5_11; -.
DR Proteomes; UP000000376; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:ADH92402.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000376};
KW Transferase {ECO:0000313|EMBL:ADH92402.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 86..250
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 295..600
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 628 AA; 67051 MW; D66C0FE90EAC60F7 CRC64;
MADYRRHEPA SLTQRIASNY RRGMGEGRGG GAVARKYTNR RLSVTIVIVL AVASLLLTRL
VYLQVFRASD LADVASSLRS QTINLEAKRG DIVDVHGNIL ATSVERYNVR ANQVELESYR
EYDKNDKLIG TGAAAAAKKL APVLGMDEAE LAGRFLGGQE KYQWELIKRD ISPDKWREIN
DLGIHGIYPE RYMQRFYPNG YVAGNILGYT GVTAEDDTVA GRAGIESTYN ELLAGKNGTL
KIEAGPSGTV FPQAPKKETP AVDGGKVKLT IDRDLQLATQ EALDSAVKKT GAEWGSAVVI
EIGTGRILAL GDSSAPDPSN LQHVNPNDWN SRAVQAVVEP GSSGKVITLS AALDAGAVHP
TDTFVVPDTL VMPNGQKISD NDNHATETMT VAGIIGKSYN TGLVQIGDRI KDKYRYSMLQ
KFGIGAKTGI ELPGETAGIL NPYESWDERT RYTTMIGQAW AASTLQLGQM ISIIGNDGVK
VPLHIVDGTY TDGGNFTPTV IGASEQVISP DAARAANQIL QGVTRSDSTG ELARVPGYNV
AGKTGTAEVP DESGNLTKRV GTFVGLLPAE KPQVAIAAVI YNASGPGYGS TTAAPVFAEI
GKFAMRSLGV APSTEPLVKF PWTQSELP
//
