ID D7BQT6_STRBB Unreviewed; 295 AA.
AC D7BQT6;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=6-phosphogluconate dehydrogenase NAD-binding protein {ECO:0000313|EMBL:ADI09303.1};
GN OrderedLocusNames=SBI_06183 {ECO:0000313|EMBL:ADI09303.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI09303.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI09303.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI09303.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
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DR EMBL; CP002047; ADI09303.1; -; Genomic_DNA.
DR RefSeq; WP_014178763.1; NC_016582.1.
DR AlphaFoldDB; D7BQT6; -.
DR STRING; 749414.SBI_06183; -.
DR KEGG; sbh:SBI_06183; -.
DR PATRIC; fig|749414.3.peg.6375; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_2_1_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000377}.
FT DOMAIN 10..158
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 166..291
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 295 AA; 31138 MW; DA17C459A58CFBAF CRC64;
MSSKTTQQSV TIIGLGPMGQ AMTTAFLDRG YAVTLWNRTP SRADALVARG ATLAPSVEEA
LAANEAVILS LTDYAAMYDV LGPAETALSG RVLVNLSSDT PEKARAAARW TAERGAVHLT
GGITVPPSGV GQPESLTFYS GPREAFDKHR DVLEVVTGRS DYRGEDPGLA ALFYQLGMVM
FWTSMLSYWQ AIALAKANGL AAADILQHAT DTANSLPGFF AFYAERIDAG NHVGDVDRLA
MGMASIDHVL HTNADSGVDT ALPAAVAGLF RRGMEAGHAA DSFSSLLDIM QKAEA
//
