ID D7BSV8_STRBB Unreviewed; 275 AA.
AC D7BSV8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=D-aminopeptidase {ECO:0000313|EMBL:ADI03135.1};
GN OrderedLocusNames=SBI_00014 {ECO:0000313|EMBL:ADI03135.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI03135.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI03135.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI03135.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
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DR EMBL; CP002047; ADI03135.1; -; Genomic_DNA.
DR RefSeq; WP_014172614.1; NC_016582.1.
DR AlphaFoldDB; D7BSV8; -.
DR STRING; 749414.SBI_00014; -.
DR KEGG; sbh:SBI_00014; -.
DR PATRIC; fig|749414.3.peg.12; -.
DR eggNOG; COG2362; Bacteria.
DR HOGENOM; CLU_086038_1_0_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08663; DAP_dppA_1; 1.
DR Gene3D; 3.30.1360.130; Dipeptide transport protein; 1.
DR Gene3D; 3.40.50.10780; Dipeptide transport protein; 1.
DR InterPro; IPR027476; DppA_N.
DR InterPro; IPR007035; Peptidase_M55.
DR InterPro; IPR036177; Peptidase_M55_sf.
DR Pfam; PF04951; Peptidase_M55; 1.
DR PIRSF; PIRSF015853; Pep_DppA; 1.
DR SUPFAM; SSF63992; Dipeptide transport protein; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:ADI03135.1};
KW Hydrolase {ECO:0000313|EMBL:ADI03135.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR015853-2};
KW Protease {ECO:0000313|EMBL:ADI03135.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Zinc {ECO:0000256|PIRSR:PIRSR015853-2}.
FT ACT_SITE 117
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-1"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 61
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 105
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 135
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
SQ SEQUENCE 275 AA; 28822 MW; CEBF348BA57D5AF5 CRC64;
MKVLISVDME GISGIVHPAE TNPDRYDYER GRALMTAEAN AVIAGVLDAE PAAEVWVADA
HGSFRNLLPE ELDRRARLVR GKPRPMGMLG GLDEHTDAVM FVGYHARAGG GPAVLAHTMS
DAILDVRVGG RSLGEIGLNA AMAGHLGVPV VLLSGDDTAC AELCDLVPSA VTVAVKEALG
QAAAVALHPE EARERLHQAA AEAVKQRTLV TPLALAGPLE VEIDLYGPYM VDLATLVPGV
SRAEGGRTVT FTAADFADAY RLVLLLVQLA SIKPG
//
