ID D7BUR7_STRBB Unreviewed; 494 AA.
AC D7BUR7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ADI03258.1};
GN OrderedLocusNames=SBI_00137 {ECO:0000313|EMBL:ADI03258.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI03258.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI03258.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI03258.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002047; ADI03258.1; -; Genomic_DNA.
DR RefSeq; WP_014172737.1; NC_016582.1.
DR AlphaFoldDB; D7BUR7; -.
DR STRING; 749414.SBI_00137; -.
DR KEGG; sbh:SBI_00137; -.
DR PATRIC; fig|749414.3.peg.140; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ADI03258.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377}.
FT DOMAIN 26..356
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 409..485
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 140..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 53628 MW; 40C2D5A37A355C44 CRC64;
MPSPQQESTE STESTVTIGE RIGQLAAEHP AATAVLSVAP NGGVSELTWA ELERLTNCAA
RGLAERGVTS RRTVAVALPA GPDHVVATVA AWKLGSLVVP LDPQGTAAER AALAAAIGEH
VLIGDVDGAA VRPGWWRERR HSDTPLPRQG TPRSATLTGG TTGLPRVIVR PRPWTYRPGA
WEARHDKAQG MRLGQTQLLV LPLYHTGFQA LYQGLALDHR VIIMERFVPS LFLKLVQEHR
VSYVRMVAAM MRMLLDVPGL RDYDLSSIET LHHGAGPCPE QVKRAWLELI DPGRVYEIYA
SQERVGRTVI RGDEWLKRPG SVGRPTDCEI RIYDEGGRQL PAGEVGEVFM RTPGVGQPSY
LGDGPRLPER DGFLTVGDLG HLDADGYLYL VDRKSNVINV GGKNVYPAEV EAVLLEMPGV
ADAVVTGRRH EYLGEAVHAL VVPSDPADPV TTAAVDAYCR ERLSDAKVPM TCQIVASVPR
QSSGKVRRAE LGER
//
