ID D7C2E5_STRBB Unreviewed; 332 AA.
AC D7C2E5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:ADI03799.1};
GN OrderedLocusNames=SBI_00678 {ECO:0000313|EMBL:ADI03799.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI03799.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI03799.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI03799.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
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DR EMBL; CP002047; ADI03799.1; -; Genomic_DNA.
DR AlphaFoldDB; D7C2E5; -.
DR STRING; 749414.SBI_00678; -.
DR KEGG; sbh:SBI_00678; -.
DR PATRIC; fig|749414.3.peg.694; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_4_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 332 AA; 34708 MW; 429B6F8D9280B9A1 CRC64;
MTRRLAEVAK KVGVSEATVS RVLNGKPGVS EATRQSVLAA LDVLGYERPT QLRGDRARLV
GLVLPELQNP IFPAFAEVIG GALAQMGLTP VLCTQTKGGV SEADYVTLLL QQQVSGVVFA
GGLYAQADAE HGHYRLLADR NIPVVLVNAA IEQLGFPGVS CDDAVAVEQA WRHLTSLGHE
RIGLVLGPGD HMPSARKLAA ARAVAGDLPD EFVARAIFSI EGGQAAASRL IDRGVTGIVC
ASDPLALGAI RAARRKGLGV PSQVSVIGYD DSALMSCTEP PLTTVRQPIE AMGRAAVELL
NAQISGLAVQ AEELPFEPEL VVRASTAQAP HG
//
