ID D7C2U8_STRBB Unreviewed; 1088 AA.
AC D7C2U8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Amidohydrolase {ECO:0000313|EMBL:ADI05981.1};
GN OrderedLocusNames=SBI_02860 {ECO:0000313|EMBL:ADI05981.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI05981.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI05981.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI05981.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the TolB family.
CC {ECO:0000256|ARBA:ARBA00009820}.
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DR EMBL; CP002047; ADI05981.1; -; Genomic_DNA.
DR RefSeq; WP_014175458.1; NC_016582.1.
DR AlphaFoldDB; D7C2U8; -.
DR STRING; 749414.SBI_02860; -.
DR KEGG; sbh:SBI_02860; -.
DR PATRIC; fig|749414.3.peg.2959; -.
DR eggNOG; COG0823; Bacteria.
DR eggNOG; COG1228; Bacteria.
DR HOGENOM; CLU_304012_0_0_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 2.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR Pfam; PF07676; PD40; 7.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 3.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ADI05981.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..1088
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003094015"
FT DOMAIN 695..1033
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT REGION 41..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1088 AA; 114317 MW; 60B15572DEFB5CF7 CRC64;
MGISRRKLIR RGGQAAAGAG SLWLGSQLTG LATAANAAEN TENTENAEQA ENADSATQTA
DGATRRITVT QATNASAALS PDGRTVVLDL LNLLWTVPAA GGEATRLTGI DQEATEPDFS
PDGRHLVYQS YTDGNFHLWL ARADGTGARR LTSGGADHRE PRFSPDGKRI AYAGEADGRY
AIHVLDLDSG ATKVWAPSTD ATVQQAQPFW RPDGKAIAFT SGKGDAPQSV VQVDADGKRT
TLATVTEGRV AGPSFSPDGA RFAYVHLASA ATALVVDGVT VSDAEEDVFP FAARWPSADE
VFYTADGKIR RRKLSGDKAR TGGAAQDIAF TAHLTVPRVQ ERPAAPDSDA APASASPRPV
KGIVSPSLSP DGERIAFAAL GDIWLAPVNP PRGKGSAPKA VVSDGHLNTD PAWSPDGSAL
VYVSDRGGAA DLWTYDIADG TTRRLTDLQD AASGPAFSPD GASVAFGLGA GTLHTVDVAT
GAVRKVAGPL NAPGRPTFSA DGRKLSLAAL APVTARYREG FNRVLTVELA TGEAHYDDPV
PGKSLANRID AGPVHSPDGK HTAYIVGGTL HLSALDTAGR PTGTARELNG ETADAPSWSA
DSRSLLYLSN GRLRLADART GRARTVPVKL TWRPAKPTGR TVVQVGAVWD GTGETLRRDV
DIVIEGDRIK AIVARGSVRA GSGGRTVDAR HLTALPGLIA VHEHGPWQRA DTMKLWLSYG
VTAVRSPGTA HYAAVEAKEA TASGRRVGPR VFAAGDLIDG SRIYYSSGRP VTDTEELERE
LAKAEALGHD LVKTYVRLPY AMQRAAIRGG HRLGLRATSH YLFGPLGLGA DGTEHLGGTS
RYGRRQKETH LGHAYDDMTE PLIASGMAFT PTFGLSGAGL PATRAALYRY AEWAVGDRRL
TTLMSEAEYE EFRSGVAAAQ QTVPTDLLAF VARHGATVRR LLEGGAHVGV GTDSPLVPPA
IYYHLNLQAM VRYGATPHQA LRSATVEGAR ALGMSARMGT VEPGKLADLV LVEGDPLSDI
RAAAAVRSVV LGGVVHSVDD LVSGESSGAA AVRPTSAATA AHVADVPQGP ARERYWWHRE
EHAHHSCC
//
