ID D7C4S5_STRBB Unreviewed; 914 AA.
AC D7C4S5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN OrderedLocusNames=SBI_03005 {ECO:0000313|EMBL:ADI06126.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI06126.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI06126.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI06126.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR EMBL; CP002047; ADI06126.1; -; Genomic_DNA.
DR AlphaFoldDB; D7C4S5; -.
DR STRING; 749414.SBI_03005; -.
DR CAZy; GH78; Glycoside Hydrolase Family 78.
DR KEGG; sbh:SBI_03005; -.
DR PATRIC; fig|749414.3.peg.3113; -.
DR eggNOG; COG3387; Bacteria.
DR HOGENOM; CLU_002926_1_1_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307:SF11; ALPHA-L-RHAMNOSIDASE; 1.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..914
FT /note="alpha-L-rhamnosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003093995"
FT DOMAIN 173..320
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 349..448
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 457..794
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 816..874
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 914 AA; 98418 MW; DB954D58CADBF2DF CRC64;
MLLAAALLPV VSTAAPGHAA AAEPRGGHAP LAPADLTVGD RARPLDVEGA PLFGWRPRDV
DPGERQTAYQ IRVARTGAGP GGSRQVWDSG KVVSARQAYV AYDGPDLPGG TGYTWTVRTW
DRTGAASPWA ARAAFDTGIS DATWQASWIR RTTGDKDDYT LARKEFTVGA SPVVRARLYV
AASQQYRAYV NGRLVDRGAA YAYPDEGYYQ AGDVTRDLKA GRPAAIGVLA HWYGPGQGRP
AGEPGLLARL VVEHADGSRQ VVVSDGSWRV ARGPWLSLPY RNDDGRDYIE GVDGRTVQRQ
RGWNRPGFDA SSWQSPQVVG VHPAGGFSHL RSQQTRLAYR TVRPVTVTRL DSGAVVADFG
TIIPAVPQVR FARGVSGRTI DMRAGYVRNA DGTVSDSAHD NQKTDLSYQY IQHDGAQTFQ
AYTYEGFRYL QIDDPGEPLS ASSIAAVVQH TDADPARAAT FRSSDPTLDA VAELMRRSAL
YDSQEQFLDT PTREKGQFLG DSVDVSRALM AGSGDRALTA RAIREFAESQ QRYWPDGRMN
AVYPNGDGKR DIPDYTEMFP GWVWEYYLNS GDRATLAATY PASAAVADYI RRYIDPATGL
VTKLAGGSGA YQYGIIDWPN RYGYDTDTTA RTTVNILAVD ALRRTADQAA ALGRPKAEAD
ALRADAAKLA EAVNDRLRRP DSLYTDGLKA DGTQSAHASQ IANAYAVAFG IAPEGSVDTI
ADHLVSLKLQ MGPMTANWLL TALHRAGRDD QVLARITDRT SLGWANILAR GGTFTWESWE
APDDGQSLSH GWGATALVDL QQDLLGLNVT GTAATTLRIR PPRDTELTHA EGTVWTQAGT
VGVRWNTTAH GTQVKVDIPV NVTAEVEVPL ADGRVPKASG AGPDGASAPR FEGVRNGRAI
YMVGSGHSTF TPAV
//
