ID D7CEA1_STRBB Unreviewed; 272 AA.
AC D7CEA1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:ADI06788.1};
GN OrderedLocusNames=SBI_03667 {ECO:0000313|EMBL:ADI06788.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI06788.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI06788.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI06788.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
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DR EMBL; CP002047; ADI06788.1; -; Genomic_DNA.
DR RefSeq; WP_014176262.1; NC_016582.1.
DR AlphaFoldDB; D7CEA1; -.
DR STRING; 749414.SBI_03667; -.
DR KEGG; sbh:SBI_03667; -.
DR PATRIC; fig|749414.3.peg.3804; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_4_3_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..75
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 76..258
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 272 AA; 29687 MW; 88590A89FAC92479 CRC64;
MAEQSPVTGT PPLQTADRVL NVLLSFDRER PEWGVTEIAA EFGLDKSVAQ RLLAALAYRG
FLVSDQRTRR YRLGPAVWHL SRVWERGGGM ASLVRPTLEA LAEAVGVSAL FAVPDGVHMR
CVAAADGATG PLRYYALAGE LYPAHAGATS RAYFGMLPPG DRAVLLYGRP MARFSENTLT
DPVRLEERFA EVRRLGYAYS EGEYDPHTAA LAVPVLVGRR PVGTLSLAAA IEELRGRWEE
LASPLQQAAA DLGRLLTPAH PRHVPPQRRD GR
//
