ID D7CIA4_STRBB Unreviewed; 504 AA.
AC D7CIA4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Putative ssp-like protease {ECO:0000313|EMBL:ADI11282.1};
GN OrderedLocusNames=SBI_08164 {ECO:0000313|EMBL:ADI11282.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI11282.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI11282.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI11282.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
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DR EMBL; CP002047; ADI11282.1; -; Genomic_DNA.
DR AlphaFoldDB; D7CIA4; -.
DR STRING; 749414.SBI_08164; -.
DR MEROPS; S08.091; -.
DR KEGG; sbh:SBI_08164; -.
DR PATRIC; fig|749414.3.peg.8399; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_011263_17_3_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..504
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003094363"
FT DOMAIN 167..494
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT REGION 102..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 175
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 219
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 426
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 504 AA; 51267 MW; 72B2E10E9F2BD8FA CRC64;
MPAGLALTAS LVLLPQAASA IPRGAPSSSA LTSSATADGP SLSYVVNTAA DHGTVGEVKK
AITASHGTVV TAYERIGVIV AHSKDPAFAK TIRQVRGVQS AGATRTAPLT PAATTEVGRP
EKVPAPRTSA ATAAKALAAG QEPLESLQWD IPAIKADQAA KVNPGSRKVT VAVIDTGVDD
THPDLAPNFS RSQSASCVGG VADTSPGAWR PWNPAEDYHG THVAGEIAAA RNGVGVAGVA
PGVKVSAIKV SEPTTSLFYA ESVVCAFVFA ADHGVEVTNN SYFVDPWKYN CAADPDQKAI
TDAVGRATAY AQRKGVVSVA SAGNSNDDLA AGSLTDTTSP NDTTPVERSV DPSVCPDVPT
QLPGVVTVSA TGVTSLKSYY SSYGLGQVDV AGPGGDKYQV PELPAKDGRI LSTLPGGDYG
YLQGTSMASP HVAGVAALLK SAHPKASPQE IQWLLKAQAD NPGCPTGPYD PDGDGDTDAV
CTGTEHINSF YGYGIVDALD AVAK
//
