ID D7CMS4_SYNLT Unreviewed; 393 AA.
AC D7CMS4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Propanoyl-CoA C-acyltransferase {ECO:0000313|EMBL:ADI02009.1};
DE EC=2.3.1.176 {ECO:0000313|EMBL:ADI02009.1};
GN OrderedLocusNames=Slip_1236 {ECO:0000313|EMBL:ADI02009.1};
OS Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC Syntrophothermus.
OX NCBI_TaxID=643648 {ECO:0000313|EMBL:ADI02009.1, ECO:0000313|Proteomes:UP000000378};
RN [1] {ECO:0000313|Proteomes:UP000000378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12680 / TGB-C1 {ECO:0000313|Proteomes:UP000000378};
RX DOI=10.4056/sigs.1233249;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Djao O., Zhang X., Lucas S., Lapidus A., Glavina Del Rio T., Nolan M.,
RA Tice H., Cheng J., Han C., Tapia R., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A.,
RA Brambilla E., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.,
RA Jeffries C., Rohde M., Sikorski J., Spring S., Goker M., Detter J.,
RA Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N.,
RA Klenk H.;
RT "Complete genome sequence of Syntrophothermus lipocalidus type strain (TGB-
RT C1T).";
RL Stand. Genomic Sci. 3:267-275(2010).
RN [2] {ECO:0000313|EMBL:ADI02009.1, ECO:0000313|Proteomes:UP000000378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12680 / TGB-C1 {ECO:0000313|Proteomes:UP000000378};
RX PubMed=21304731;
RA Djao O.D., Zhang X., Lucas S., Lapidus A., Del Rio T.G., Nolan M., Tice H.,
RA Cheng J.F., Han C., Tapia R., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A.,
RA Brambilla E., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Rohde M., Sikorski J., Spring S., Goker M., Detter J.C.,
RA Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Syntrophothermus lipocalidus type strain (TGB-
RT C1).";
RL Stand. Genomic Sci. 3:268-275(2010).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP002048; ADI02009.1; -; Genomic_DNA.
DR RefSeq; WP_013175411.1; NC_014220.1.
DR AlphaFoldDB; D7CMS4; -.
DR STRING; 643648.Slip_1236; -.
DR KEGG; slp:Slip_1236; -.
DR eggNOG; COG0183; Bacteria.
DR HOGENOM; CLU_035425_4_0_9; -.
DR OrthoDB; 9785768at2; -.
DR Proteomes; UP000000378; Chromosome.
DR GO; GO:0033814; F:propanoyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0050632; F:propionyl-CoA C2-trimethyltridecanoyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00829; SCP-x_thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR PANTHER; PTHR42870; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR42870:SF6; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:ADI02009.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000378};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:ADI02009.1}.
FT DOMAIN 11..191
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 260..356
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 393 AA; 42747 MW; 4A0F7A5467B75B9C CRC64;
MAAGIKDKAA VIGMGCTKFG ERFDCNLEDL MLEAIEEALA DSGLEFNDID AFWFGTFTSG
MAGLAFSNRM KSQYKPVTRI ENMCCTGLDA FRNACYAVVS GAYDVVMAIG AEKLKDGGYS
GLEVPAEDSD RTMPDLTAPA RFAVIAPAYA HKYGLSMQQM KEVMARIAWK NHKNGSLNPK
AQFQAEVPIE NILKSPMICS PLGIMDCSGV SDGAACAIIV RSEDAKKYRP DPMYVKGIQI
AAGPGHSEKH QSYDFTTAWE TYYAGQAAYR EAGITNPREQ IDLAEVHDCF TPTELIIYED
LQFSARGQGW RDALDGFFDL DGKLPVNPDG GLKSFGHPIG ASGIRMLYES WLQFHGKAGK
RQLENPKIGL AHNLGGQPYQ CVVGVAVVGK ELG
//
