ID D7E0L5_NOSA0 Unreviewed; 500 AA.
AC D7E0L5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ADI64671.1};
GN OrderedLocusNames=Aazo_2825 {ECO:0000313|EMBL:ADI64671.1};
OS Nostoc azollae (strain 0708) (Anabaena azollae (strain 0708)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
OC Trichormus.
OX NCBI_TaxID=551115 {ECO:0000313|EMBL:ADI64671.1, ECO:0000313|Proteomes:UP000001511};
RN [1] {ECO:0000313|EMBL:ADI64671.1, ECO:0000313|Proteomes:UP000001511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0708 {ECO:0000313|EMBL:ADI64671.1,
RC ECO:0000313|Proteomes:UP000001511};
RX PubMed=20628610; DOI=10.1371/journal.pone.0011486;
RA Ran L., Larsson J., Vigil-Stenman T., Nylander J.A., Ininbergs K.,
RA Zheng W.W., Lapidus A., Lowry S., Haselkorn R., Bergman B.;
RT "Genome erosion in a nitrogen-fixing vertically transmitted endosymbiotic
RT multicellular cyanobacterium.";
RL PLoS ONE 5:E11486-E11486(2010).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP002059; ADI64671.1; -; Genomic_DNA.
DR RefSeq; WP_013191687.1; NC_014248.1.
DR AlphaFoldDB; D7E0L5; -.
DR STRING; 551115.Aazo_2825; -.
DR KEGG; naz:Aazo_2825; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_2_3; -.
DR OrthoDB; 505602at2; -.
DR Proteomes; UP000001511; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001511};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..124
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 267..404
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 169..227
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 500 AA; 54006 MW; FA286B7E43B5CB5C CRC64;
MTTYIQIPLI GKKVKHPLRW LMGLITAGVL VVGTTTVLKV THQNTNKQDI SKLTVPVVAK
SVTVRITASG KVQPVQSVNI SPKNPGIITD LDIEQGEKVQ KGQIIARMDN SEIKMRILQY
QANVEEAKAQ LAESLAGSRP EEIAQAKARV AQAKAQLAII RGGNRSQEID QAKAAVDSAK
AQVELTQARV KRYQGLAKAG AISQDSLEQY ISENKRSKAS LEEAQARLSL QKAGNRNEDI
KSQEAVVAQE QETMGKLENG NRPEEIARLK ASVAGAVAQL KQQEVQLEDT IIRAPFAGVV
TQKYANIGAF VTPTTSASTS TSATSSSIVA LAMGLEVLAQ VPEADIGRIS QGQQVEIVAD
TYPDQVFKGR VRLIAPEAVV EQGVTSFQVR VVIDSGADKL RSGLNVDLTF LGDRINDALT
LPTVAILTEN GKTGVLIADA NNKPQFREIT IGTQIKDETQ VLEGVKKGDL IFVNPPKDYK
IQKAKEEKNH ELPRKHSNGG
//
