ID D7E311_NOSA0 Unreviewed; 603 AA.
AC D7E311;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=GTP-binding protein LepA {ECO:0000313|EMBL:ADI65079.1};
GN OrderedLocusNames=Aazo_3444 {ECO:0000313|EMBL:ADI65079.1};
OS Nostoc azollae (strain 0708) (Anabaena azollae (strain 0708)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
OC Trichormus.
OX NCBI_TaxID=551115 {ECO:0000313|EMBL:ADI65079.1, ECO:0000313|Proteomes:UP000001511};
RN [1] {ECO:0000313|EMBL:ADI65079.1, ECO:0000313|Proteomes:UP000001511}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0708 {ECO:0000313|EMBL:ADI65079.1,
RC ECO:0000313|Proteomes:UP000001511};
RX PubMed=20628610; DOI=10.1371/journal.pone.0011486;
RA Ran L., Larsson J., Vigil-Stenman T., Nylander J.A., Ininbergs K.,
RA Zheng W.W., Lapidus A., Lowry S., Haselkorn R., Bergman B.;
RT "Genome erosion in a nitrogen-fixing vertically transmitted endosymbiotic
RT multicellular cyanobacterium.";
RL PLoS ONE 5:E11486-E11486(2010).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. LepA subfamily.
CC {ECO:0000256|ARBA:ARBA00005454}.
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DR EMBL; CP002059; ADI65079.1; -; Genomic_DNA.
DR RefSeq; WP_013192093.1; NC_014248.1.
DR AlphaFoldDB; D7E311; -.
DR STRING; 551115.Aazo_3444; -.
DR KEGG; naz:Aazo_3444; -.
DR eggNOG; COG0481; Bacteria.
DR HOGENOM; CLU_009995_3_3_3; -.
DR OrthoDB; 580826at2; -.
DR Proteomes; UP000001511; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd03699; EF4_II; 1.
DR CDD; cd16260; EF4_III; 1.
DR CDD; cd01890; LepA; 1.
DR CDD; cd03709; lepA_C; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.2570; Elongation factor 4, C-terminal domain; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR HAMAP; MF_03138; GUFP; 1.
DR HAMAP; MF_00071; LepA; 1.
DR InterPro; IPR006297; EF-4.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027518; GUFP.
DR InterPro; IPR038363; LepA_C_sf.
DR InterPro; IPR013842; LepA_CTD.
DR InterPro; IPR035654; LepA_IV.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR NCBIfam; TIGR01393; lepA; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43512:SF4; TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43512; TRANSLATION FACTOR GUF1-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF06421; LepA_C; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00022519};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001511}.
FT DOMAIN 7..190
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 603 AA; 67529 MW; 92715AFD68F39DD4 CRC64;
MTDVPAVRIR NFCIIAHIDH GKSTLADRLL QATGTVEDRQ MKEQFLDNMD LERERGITIK
LQAARMNYTA KDGQQYVLNL IDTPGHVDFS YEVSRSLAAC EGALLVVDAS QGVEAQTLAN
VYLALEHNLE IIPVLNKIDL PGAEPDRVIG EIEEIIGLDC SGAILASAKE GIGVPEILEA
IVERVPPAPD RVNERLRALI FDSYYDSYRG VIVYFRVMDG SVKKGDRIYL MASSKEYDID
ELGILSPTQK QVEELHAGEV GYLAASIRAV ADARVGDTIT LAKAKATEAL PGYTEAKPMV
FCGMFPIDAD QFEDLREALE KLELNDAALH YEPETSSAMG FGFRCGFLGL LHMEIVQERL
EREYNLDLII TAPSVVYKVI TIKSEEVYID NPSRLPSPNE RERIEEPYVQ VEMITPETYV
GSLMELSQNR RGVFKDMKYL TQGRTTLTYE LPLAEVVTDF FDQMKSRSRG YASMEYHLIG
YRENPLVKLD IMINGDPVDS LAMIVHRDKA YNVGRSMAEK LKELIPRHQF KVPIQASIGS
KVIASEHIPA LRKDVLAKCY GGDISRKKKL LQKQAKGKKR MKSVGTVDVP QEAFMAVLRL
DQN
//
