ID D7E6G6_METEZ Unreviewed; 444 AA.
AC D7E6G6;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:ADI73188.1};
GN OrderedLocusNames=Metev_0260 {ECO:0000313|EMBL:ADI73188.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI73188.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI73188.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
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DR EMBL; CP002069; ADI73188.1; -; Genomic_DNA.
DR RefSeq; WP_013193756.1; NC_014253.1.
DR AlphaFoldDB; D7E6G6; -.
DR STRING; 644295.Metev_0260; -.
DR GeneID; 9345873; -.
DR KEGG; mev:Metev_0260; -.
DR HOGENOM; CLU_046525_0_1_2; -.
DR OrthoDB; 27588at2157; -.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000000391}.
FT DOMAIN 2..129
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 141..222
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 229..350
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 364..444
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 444 AA; 48108 MW; 1CFFD665C1C754FA CRC64;
MKIVIIGAGE VGYHIANSLY ENNDVIIIDR DDEACERADE LDLQVIQGNG ANVRLLTQVL
TNADLLVAVT GSDEVNIVSC MAAKLVSKSK KPLKTMARVS NPDYIDKPVA RRTQIGIDTM
ICPELAMASE VAEVLSIPSA IDAEFFADGK VEMIEFVAKD NTEIVGKQVK NLQLSESCII
SALFRGGEVI IPHGDDAINS GDHVVIIGKT DEMKSIRGIF GEIGQNVNKV MIIGGGKVGF
HLAQIAQKSG IKIKIIEHDK KRCEYIADVL PEVLVINGDG TDVNLLKEEE VSNMDTVFSV
MDSDEKNLLS ALLAKQFGVG KVIARVERSG YSPLFEMVGV DLAASPKQAT INEVMKLSMG
TGIEALTTIE GERAEIIEYI AYKNSKITGK PLKDIKFPSG AIVSMVIHGN EPFIPRGDHV
IEDGDRVLIF SLPSAVTDVE KLFK
//
