ID D7E946_METEZ Unreviewed; 448 AA.
AC D7E946;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Transposase, IS605 OrfB family {ECO:0000313|EMBL:ADI73994.1};
GN OrderedLocusNames=Metev_1112 {ECO:0000313|EMBL:ADI73994.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI73994.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI73994.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
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DR EMBL; CP002069; ADI73994.1; -; Genomic_DNA.
DR RefSeq; WP_013194561.1; NC_014253.1.
DR AlphaFoldDB; D7E946; -.
DR STRING; 644295.Metev_1112; -.
DR GeneID; 9346744; -.
DR KEGG; mev:Metev_1112; -.
DR HOGENOM; CLU_032903_0_1_2; -.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000000391};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 13..52
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 207..320
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 332..402
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
FT COILED 247..274
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 448 AA; 51392 MW; 3B101970CE2DC4BD CRC64;
MESIVRKEGQ NCRNLRFKIH PTLEQEKKLN ETLEYCRSTW NHLLSIRVDL YDRFDLSVSK
SSLEKYLKNL DYPIHSSVRL DVFQRLCSAY DKFFDDIKNG RLKNTKPKKG MFVKRKDIPC
GNNSSGFIKY DGILPKGHPK FKSKEDFSSF RYKQHGNGWK LEDNKLYLSK ITGKSNLIKI
DIDRLPDGEL KTCTLKKEGK QWFAYLTVEL PENPVPSTPE NAVGIDLGLK SFITTSNDDF
VEPPRFLRKA EKRLAKEQRK LSRMEFKSNN YKKQKQKVNR IHRKVASARN HFSHCLSKLL
VEKYDLIVFE DLKIKNLVKN NKLAKSISDV SWNKLVQHVT YKAAERGKIV DKINPDNTTQ
VCSHCGTKKK EKLRLGDRIF YCSKCGLEID RDLNAAVNIL TKSSYYNPMH TVGLAGMNGC
GDGASTTGLG IGSQVPPMNQ QTLNLLRG
//
