ID D7FRE2_ECTSI Unreviewed; 279 AA.
AC D7FRE2;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 03-MAY-2023, entry version 33.
DE RecName: Full=Checkpoint protein {ECO:0000256|PIRNR:PIRNR011312};
GN ORFNames=Esi_0213_0040 {ECO:0000313|EMBL:CBJ30733.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ30733.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ30733.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SIMILARITY: Belongs to the HUS1 family. {ECO:0000256|ARBA:ARBA00005563,
CC ECO:0000256|PIRNR:PIRNR011312}.
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DR EMBL; FN648391; CBJ30733.1; -; Genomic_DNA.
DR AlphaFoldDB; D7FRE2; -.
DR STRING; 2880.D7FRE2; -.
DR EnsemblProtists; CBJ30733; CBJ30733; Esi_0213_0040.
DR eggNOG; KOG3999; Eukaryota.
DR InParanoid; D7FRE2; -.
DR OMA; VCWMRLE; -.
DR OrthoDB; 37457at2759; -.
DR Proteomes; UP000002630; Chromosome LG11.
DR GO; GO:0030896; C:checkpoint clamp complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:InterPro.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR016580; Cell_cycle_HUS1.
DR InterPro; IPR007150; Hus1/Mec3.
DR PANTHER; PTHR12900:SF0; CHECKPOINT PROTEIN; 1.
DR PANTHER; PTHR12900; MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1; 1.
DR Pfam; PF04005; Hus1; 1.
DR PIRSF; PIRSF011312; Cell_cycle_HUS1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
SQ SEQUENCE 279 AA; 30867 MW; 721A25011ADEC7FF CRC64;
MRFKAKIVQD KLLAFAGVIG AIEKIGTACV VHLTETRVHL SVQESGSEGV DVYAELIQDM
LFHEYRIESR AGNAILFEAN ASLLLQALNS GKTSPTCQIK LAKRAGQPCL SIETRALEIE
VVHDIPVKVM PANEAEYYLP PKVHSPQVQL ELPRQRSLRT VVDRMKAIDK FLFVDADMGG
QLVFRVEKAD ATIKTFYSNL TPRFEEMDAN TCRKNMSSVK VDVKKLAAVM SMYALRFDTA
ICCIIGGYSL VLHVILSPIN IGNLTYYVPV MDAGDDLAA
//
