ID D7FX06_ECTSI Unreviewed; 352 AA.
AC D7FX06;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Cathepsin Z-like proteinase {ECO:0000313|EMBL:CBJ26339.1};
GN ORFNames=Esi_0032_0024 {ECO:0000313|EMBL:CBJ26339.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ26339.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ26339.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; FN648509; CBJ26339.1; -; Genomic_DNA.
DR AlphaFoldDB; D7FX06; -.
DR STRING; 2880.D7FX06; -.
DR EnsemblProtists; CBJ26339; CBJ26339; Esi_0032_0024.
DR eggNOG; KOG1543; Eukaryota.
DR InParanoid; D7FX06; -.
DR OMA; GFMDIDH; -.
DR OrthoDB; 5475703at2759; -.
DR Proteomes; UP000002630; Chromosome LG04.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF679; PEPT_C1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 21..267
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 38636 MW; B4D564DEAD343517 CRC64;
MLEAPPHGHA KQSPTIPESS LPDTFDWSDV DGRSYLLPSW NQHIPTYCGS CYVHAALSVV
QDRIKVAKGG RPPDVMLARQ SFINCGEAHG FGKGCGGGNA PDVYNFMHEV GLPDETCNAY
VAKESDTCDA EAMCKNCMVQ ADGSHECWAV ERQSRYYVTE WGTIEGGEEA MMSEIFSRGP
IGCALFSDDA FDYDYEGGVH TAQVTGNLTV ADVNHDVEVT GWGVTNDGVK FWQARNSWGT
FWGEQGFFKI QRGVNLNFIE SECYFPVPEY GDESLLADGD LTGSLHGLVP KGDKASAEGV
FFRQQLAKLD WTALKTPPIL LAADALRDGW KNARTWSLSS RMGRVRHVQP GT
//
