ID D7G482_ECTSI Unreviewed; 1410 AA.
AC D7G482;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Lipase domain protein {ECO:0000313|EMBL:CBJ27097.1};
GN ORFNames=Esi_0055_0048 {ECO:0000313|EMBL:CBJ27097.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ27097.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ27097.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648763; CBJ27097.1; -; Genomic_DNA.
DR STRING; 2880.D7G482; -.
DR EnsemblProtists; CBJ27097; CBJ27097; Esi_0055_0048.
DR eggNOG; KOG4569; Eukaryota.
DR InParanoid; D7G482; -.
DR OrthoDB; 91669at2759; -.
DR Proteomes; UP000002630; Chromosome LG15.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004620; F:phospholipase activity; IEA:UniProt.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd00519; Lipase_3; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002921; Fungal_lipase-like.
DR PANTHER; PTHR45856; ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR45856:SF11; LIPASE_3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01764; Lipase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 620..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1211..1314
FT /note="Fungal lipase-like"
FT /evidence="ECO:0000259|Pfam:PF01764"
FT REGION 134..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 773..1104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 978..1006
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1074..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1410 AA; 149773 MW; 41A644405655C84C CRC64;
MQSTCNRRKT VSACVSLLGI RPAKPLKHGE ENNRHQIFYK HGVRLVEAAE IQLESLGSPA
TYAVFILPYL LLALALWLDM GKLDVTSRLF PPSGNACDDS GVCSWNVTGA PIHNSFLVVK
GDFDFEVVDG LVTPSPSDGV ATGGGGGGGG GGGGEGDAVD GQEGAGGQRS RRGLAIEDVG
GGDEEMTEGR RRGLMLPFRN RGVQQDADDD VEQLALGVAL EILNCHPSEM ECDTSTLGRV
VLDSIGIIGH HSEYAVKATI LAIQGGQPIL GGGGLVARST TFKVETESRV YSEVRSMARL
PLLALTAFLL LYWMTRGFGG AGGERDPAPS AIVPERRYIT MLLFGLLLWQ NPVMAVEDWL
LGPSSFDTGP WRWVQLCRDL CQFTGMQVMW LCWICLMDGQ HFVRKRSQRS DSSFDGSATA
AGVAYRQVAG EDGDASVDTK GGESAASPCF LKDDYPPHHP KSDSFIDFIL PKVLYGFLSL
LVGVAVMLLR HPYLARLDQV DWLNGLFELS YAMMSMVSGL LWLGWTMYFA AVAVTSGRVL
RGQPFFGTRR QQLSYRVMVM QGMLVAVLFG MSVGVDIFYL VGHLLRQQVV VGASTGFTLK
SMTSAAAGLS AWTGGIRQPL GKLILVSAVC YNVAYLFLPP THSVKRLFDR MYINMERDMP
PREVVRRYKD SQELSPLFCV ETSCFLVEVA WQAYYDPHKV DLSDFVAPGR QDLSYLGLEL
VAYFNDEKHE IRAILCRGED RLILAFRGTA RMENLMTDLK FHQVPLPQLL PPGREPIEIQ
LPDGNSRRYS NVFSDNDAQR DSRSYSNNST SKRNRSRNFD GGVGSGDGPS WSRSDVSRSR
SPARSSATAA APRGARRAEA ARFSPARVGR GLSPTNRPAA AAAAAAAAAT KTPASPRKVV
SDSTPRGVEG RSAPEGGGAS RGGGEGEEAA GAAAPGGGDG GAASGATSSL PEAGATPSVA
EAGGGGEGAG TDGEEQGSEG GVSRDESVAR REKQPGAGDA ADDETCKPEQ AAATGAPAPS
RPKNPNDLVR LFMSESGGGS NGRAHTVGGG GGGDGGGGGG GGGRVVDSQS AAASAPADVG
SGTNSADGGN GTDNDSKDGH VDVEGDADAD AQQHVPAAGD GQEEGQGLEG QHWADGSSVG
GGGDSDGESK FGGDAYNNDA VGDGDDLEAA GGNFGEGDFH IDPRGDGSFT TTAARCFKAV
IHRIPVARQA LPRVHGGFWE AYSVLRERVL AALAAEMQDD YRPLYVTGHS LGGALASLAA
YDIDKNFTLP DPTTLYTFGS PRVGNGVFAR KLDSRVKHHF RLVNDGDLIT ALPRFFGTYK
HAGCKVVVDS ERYGNFIVAP TLVEQTFGAK PLASLTPHLL NQYRECLEAC MEEADLEDYF
SRGIGVDPTL VPEWLKGRRR RRKEDEPALL
//
