ID   D7G716_ECTSI            Unreviewed;       461 AA.
AC   D7G716;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Sulfotransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=Esi_0008_0148 {ECO:0000313|EMBL:CBJ25709.1};
OS   Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC   Ectocarpales; Ectocarpaceae; Ectocarpus.
OX   NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ25709.1, ECO:0000313|Proteomes:UP000002630};
RN   [1] {ECO:0000313|EMBL:CBJ25709.1, ECO:0000313|Proteomes:UP000002630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX   PubMed=20520714; DOI=10.1038/nature09016;
RA   Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA   Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA   Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA   Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA   Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA   Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA   Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA   Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA   Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA   Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA   Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA   Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA   Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA   Yamagishi T., Van de Peer Y., Wincker P.;
RT   "The Ectocarpus genome and the independent evolution of multicellularity in
RT   brown algae.";
RL   Nature 465:617-621(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC       pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
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DR   EMBL; FN649035; CBJ25709.1; -; Genomic_DNA.
DR   AlphaFoldDB; D7G716; -.
DR   EnsemblProtists; CBJ25709; CBJ25709; Esi_0008_0148.
DR   eggNOG; ENOG502S47N; Eukaryota.
DR   InParanoid; D7G716; -.
DR   OrthoDB; 116536at2759; -.
DR   Proteomes; UP000002630; Chromosome LG02.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR   PANTHER; PTHR12129:SF15; URONYL 2-SULFOTRANSFERASE; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..461
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003095876"
FT   REGION          56..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..143
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   461 AA;  50523 MW;  17799188B5D267A1 CRC64;
     MRASFLPPWS KIALCVFACV CSLAYLSKAA VHPAIVAPPK PDDASSAEGQ YSAEGRFSAE
     GQHSARGRHS AEERHSAEDR YGAAPRPQQA AAAEEEEETK AAAPGVLEVG ATTPGSAVEE
     GHGSLRSREG EVQEGKSHED GIDGTPDGGV ALAGDGASRS AASVAATVQS PASPGQCWVF
     MHLQKCGGST VKDLLEDRWG SRFFIYDSMR WKFGDEFSAK FGAKLALGDK WNVMTGGYTE
     ALRLSEPVGA GCRFFTLFRH PIARMVSAYF YCRSVSGDVA CASEVMQAKD VDLLTFAKHW
     GNFALRQFAL GFVPSDDVQE YQLKMYLERP QKEDGGVLGQ REAMTAHQDA AATPDAPLYE
     LLQPAMDLVR DGYVAVGILE QWNTTLRLFD HTLDMPVMNW EEQFAESGKH HVDIVNKQLE
     IETLQQAWTD SELKKYMRLD LLLYEHAVDV FHQQARSHGL L
//