ID D7GSY5_9FIRM Unreviewed; 565 AA.
AC D7GSY5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Putative regulator of cell autolysis {ECO:0000313|EMBL:CBL40927.1};
DE EC=2.7.13.3 {ECO:0000313|EMBL:CBL40927.1};
GN ORFNames=CK3_11890 {ECO:0000313|EMBL:CBL40927.1};
OS butyrate-producing bacterium SS3/4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=245014 {ECO:0000313|EMBL:CBL40927.1, ECO:0000313|Proteomes:UP000008961};
RN [1] {ECO:0000313|EMBL:CBL40927.1, ECO:0000313|Proteomes:UP000008961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SS3/4 {ECO:0000313|EMBL:CBL40927.1,
RC ECO:0000313|Proteomes:UP000008961};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Clostridiales sp. SS3/4.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL40927.1, ECO:0000313|Proteomes:UP000008961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SS3/4 {ECO:0000313|EMBL:CBL40927.1,
RC ECO:0000313|Proteomes:UP000008961};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP929062; CBL40927.1; -; Genomic_DNA.
DR AlphaFoldDB; D7GSY5; -.
DR KEGG; bprs:CK3_11890; -.
DR PATRIC; fig|245014.3.peg.2913; -.
DR HOGENOM; CLU_020473_3_3_9; -.
DR BioCyc; BBAC245014:G1314-1013-MONOMER; -.
DR Proteomes; UP000008961; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 1.10.1760.20; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CBL40927.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..189
FT /note="Signal transduction histidine kinase 5TM receptor
FT LytS transmembrane region"
FT /evidence="ECO:0000259|Pfam:PF07694"
FT DOMAIN 364..442
FT /note="Signal transduction histidine kinase internal
FT region"
FT /evidence="ECO:0000259|Pfam:PF06580"
FT DOMAIN 460..561
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 565 AA; 62654 MW; B05A9A77B4F7B95F CRC64;
MTGTMFFNML LNIGLLVLLA TLLTNMASVR KLFRGENSTI AQKMALAVIF GAISIVSTYT
GTKTGGAIVN TRVIGVLTAG IMGGPFVGMM TALIAGAHRF LFDIGGFTAA SCAVSTLVEG
VLGSLVYKKY KTGEMDSVDL FFLTAEAEIL QMVIILMISK PLGAAMELVG KIAVPMIVMN
SVGMVLFFKT FDMVYMREDS LFAERMRLSM GIADKSLVYL RKGFGKRENM EAVTDIIFGE
IPCQAVIITD EKEVLAVSSL IDDSRFRREK FLEHLTGPAK GMKAECIWEE DLDEEIRPLF
HSLVTVTVPV MTGDEKIGSL SIVVKKRRRV ERSIGDFLEE LAKMFSTQLG VYNVEYQKKL
RKKAEFKALQ SQVNPHFLYN ALNTISCICD EDAGKASDLI LTLASYYRQT LENDQYMLDI
DTEINHVRTY LEIEKARFEE KLRVEINVED GLSCQVPSFI LQPIVENAVR YGNSADGMRR
VEISAKRVQS GTGEELVRIG VRDHGKGFEP EEAERILTGN KTGSVGLKNV NERLKSTYGK
RYGLEIRNTD DGAEVSFCIP YQAAG
//
