ID D7KP48_ARALL Unreviewed; 396 AA.
AC D7KP48;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 55.
DE SubName: Full=Chalcone synthase family protein {ECO:0000313|EMBL:EFH65598.1};
GN ORFNames=ARALYDRAFT_470071 {ECO:0000313|EMBL:EFH65598.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; GL348713; EFH65598.1; -; Genomic_DNA.
DR RefSeq; XP_002889339.1; XM_002889293.1.
DR AlphaFoldDB; D7KP48; -.
DR STRING; 81972.D7KP48; -.
DR EnsemblPlants; fgenesh2_kg.1__25__AT1G02050.1; fgenesh2_kg.1__25__AT1G02050.1; fgenesh2_kg.1__25__AT1G02050.1.
DR GeneID; 9325403; -.
DR Gramene; fgenesh2_kg.1__25__AT1G02050.1; fgenesh2_kg.1__25__AT1G02050.1; fgenesh2_kg.1__25__AT1G02050.1.
DR KEGG; aly:9325403; -.
DR eggNOG; ENOG502QSSY; Eukaryota.
DR HOGENOM; CLU_034992_2_0_1; -.
DR OrthoDB; 460049at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:EnsemblPlants.
DR GO; GO:0090439; F:tetraketide alpha-pyrone synthase activity; IEA:EnsemblPlants.
DR GO; GO:0030639; P:polyketide biosynthetic process; IEA:EnsemblPlants.
DR GO; GO:0080110; P:sporopollenin biosynthetic process; IEA:EnsemblPlants.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 16..236
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 245..393
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 172
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 396 AA; 43797 MW; EAD84B80903BAB6B CRC64;
MSNSRMNGVE KLSSISTRRV ANPGKATLLA LGKAFPSQVV PQENLVEGFL RDTKCEDAFI
KEKLEHLCKT TTVKTRYTVL SREILDKYPE LTTEGSPTIK QRLEIANEAV VEMALEASLG
CIKEWGRPVE DITHIVYVSS SEIRLPGGDL YLSAKLGLRN DVNRVMLYFL GCYGGVTGLR
VAKDIAENNP GSRVLLTTSE TTILGFRPPN KARPYDLVGA ALFGDGAAAV IIGADPRECE
APFMELHYAV QQFLPGTQNV IDGRLTEEGI NFKLGRDLPQ KIEENIEEFC KKLMGKAGGD
ESMEFNDMFW AVHPGGPAIL NRLETKLKLE KEKLESSRRA LVDYGNVSSN TILYVMEYMR
EELKKKGDEA QEWGLGLAFG PGITFEGLLI RSLTSP
//
