ID   D7KVL0_ARALL            Unreviewed;       787 AA.
AC   D7KVL0;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=ARALYDRAFT_315769 {ECO:0000313|EMBL:EFH63387.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; GL348714; EFH63387.1; -; Genomic_DNA.
DR   RefSeq; XP_002887128.1; XM_002887082.1.
DR   AlphaFoldDB; D7KVL0; -.
DR   STRING; 81972.D7KVL0; -.
DR   EnsemblPlants; fgenesh1_pm.C_scaffold_2000802; fgenesh1_pm.C_scaffold_2000802; fgenesh1_pm.C_scaffold_2000802.
DR   GeneID; 9323193; -.
DR   Gramene; fgenesh1_pm.C_scaffold_2000802; fgenesh1_pm.C_scaffold_2000802; fgenesh1_pm.C_scaffold_2000802.
DR   KEGG; aly:9323193; -.
DR   eggNOG; KOG0167; Eukaryota.
DR   HOGENOM; CLU_006348_4_1_1; -.
DR   OrthoDB; 2721872at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR006911; ARM-rpt_dom.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR23315:SF284; U-BOX DOMAIN-CONTAINING PROTEIN 7; 1.
DR   Pfam; PF04826; Arm_2; 1.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00185; ARM; 5.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
DR   PROSITE; PS51698; U_BOX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          276..350
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
FT   REPEAT          471..517
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          712..758
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        712..732
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   787 AA;  87083 MW;  639D7DE54EE45486 CRC64;
     MDVTELEENL FAASDAKLHG DMCKELSGVL CKVLSIFPSL EGARPRSKSG IQALCSLHIA
     LEKAKNILQH CSECSKLYLA ITGDAVLLKF EKAKIALIDG LKRVEDIVPS SIGSQILEIV
     GELENTRFML DPSEKEVGDQ IIALLQQGKK FDNCNDNTEL EIFHRAATRL SITSSRVALA
     ERRALKKLID RARAEEDKRK ESIVAYLLHL MRKCSKLFRS EILDENDSQG SYPCSPTVQG
     FNEDRGSVHG FGRQLSRFGS LNDKPMNSIN SGQMPVPPEE LRCPISLQLM CDPVIIASGQ
     TYERVCIEKW FSDGHNTCPK TQQQLPHLSL TPNNCVKGLI ASWCEQNGTQ IPSGPPESQD
     LDYWRLALSD SESTKSQSVN SIGSCKLKGI KIVPLEENGT TVVERQNTEE SFVSDDDDDE
     DSDLHVLERY QDLLTILNEE EDLEKKGKVV EKIRLLLKDD EEARIFMGAN GFVEALLRFL
     GSAVDENNAS AQDSGAMALF NLAVNNNRNK ELMLTFGVIP LLEKMISSSE SQGSATALYL
     NLSCLDEAKS VIGSSQAVPF LVQLLQREIE TQCKLDALHA LYNLSTYSPN IPALLSTNII
     KSLQGLLTST GENLWTEKSL AVLLNLASSQ EGKDEAVSSQ GMISSLATVL DMGDTTEQEQ
     AVSCLLILCN GRESCIQMVL QEGVIPSLVS ISVNGTPRGR EKSQKLLMLF REQRQQRDQP
     SPNRDKPPQK EPPRKSLSAP MSVHGSNPAS APVPDYEPRF LSKSMSRRKS LARPFSFLWK
     KSYSVRE
//