ID D7KVM9_ARALL Unreviewed; 652 AA.
AC D7KVM9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350, ECO:0000256|PIRNR:PIRNR038922};
GN ORFNames=ARALYDRAFT_475871 {ECO:0000313|EMBL:EFH64875.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC ribonucleoprotein complex that mediates the cotranslational targeting
CC of secretory and membrane proteins to the endoplasmic reticulum (ER).
CC {ECO:0000256|PIRNR:PIRNR038922}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR038922}. Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}.
CC -!- SIMILARITY: Belongs to the SRP72 family.
CC {ECO:0000256|ARBA:ARBA00007676, ECO:0000256|PIRNR:PIRNR038922}.
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DR EMBL; GL348714; EFH64875.1; -; Genomic_DNA.
DR RefSeq; XP_002888616.1; XM_002888570.1.
DR AlphaFoldDB; D7KVM9; -.
DR STRING; 81972.D7KVM9; -.
DR EnsemblPlants; fgenesh2_kg.2__1001__AT1G67680.1; fgenesh2_kg.2__1001__AT1G67680.1; fgenesh2_kg.2__1001__AT1G67680.1.
DR GeneID; 9323204; -.
DR Gramene; fgenesh2_kg.2__1001__AT1G67680.1; fgenesh2_kg.2__1001__AT1G67680.1; fgenesh2_kg.2__1001__AT1G67680.1.
DR KEGG; aly:9323204; -.
DR eggNOG; KOG2376; Eukaryota.
DR HOGENOM; CLU_013808_2_0_1; -.
DR OrthoDB; 91080at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-UniRule.
DR GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR InterPro; IPR026270; SRP72.
DR InterPro; IPR031545; SRP72_TPR-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR Pfam; PF08492; SRP72; 1.
DR Pfam; PF17004; SRP_TPR_like; 1.
DR PIRSF; PIRSF038922; SRP72; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038922};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR038922};
KW Signal recognition particle {ECO:0000256|ARBA:ARBA00023135,
KW ECO:0000256|PIRNR:PIRNR038922}.
FT DOMAIN 544..597
FT /note="Signal recognition particle SRP72 subunit RNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF08492"
FT REGION 538..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 71146 MW; F72F4BF06281936C CRC64;
MAPKSKEKSK TSTSQPPLAI EDLFSSLNGH IQGSEFEEAV KVADKVLSIL PTDEDAIRCK
VVALIKDDKI DGALSVISSF QKLPIDLGFQ NAYCLYRLNK LDEALVCLKG LERDSDTLLL
ESQILYRLGK ADACVDVCQK LSKSEIESLE INLVAALITA GKASQVPKAL EGLKIKPTST
YDLAYNTACS LIENNNYADA EQLLLTAKRI GQETLTEDDC SDEYIETELA PISVQLAYVQ
QVLGQTQEST SSYVDIIKRN LADEPSLAVA VNNLVASKGS KDISDGLRKF DRLKEKDSQN
FQLSQELDAK LSQKNKEAIY ANRVLLLLHA NKMDQARELS AALPGMFPES VIPTLLQAAV
LVRENKAAKA EELLGQCAEK FPEKSKLVLL ARAQIAASAS HPHVAAESLS KIPDIQHLPA
TVATIVALKE RAGDNDGAAA VLDSAIKWWS NSMTESNKLS VMMPEAAAFK LRHGQEEEAS
RLYEEIVKNH NSTDALVGLV TTLARVNVEK AETYEKQLKP LPGLKAVDVD NLEKTSGAKP
IEGAAASSSQ EEVKKEKAKR KRKRKPKYPK GFDPANPGPP PDPERWLPRR ERSSYRPKRK
DKRAAQIRGS QGAVTKDKQE AAPSTSKSNQ AASSKANAAA PSSKASKKKS RR
//
