ID D7KY54_ARALL Unreviewed; 584 AA.
AC D7KY54;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
DE EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};
GN ORFNames=ARALYDRAFT_338459 {ECO:0000313|EMBL:EFH64472.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8; Evidence={ECO:0000256|PROSITE-
CC ProRule:PRU00277};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL348714; EFH64472.1; -; Genomic_DNA.
DR RefSeq; XP_002888213.1; XM_002888167.1.
DR AlphaFoldDB; D7KY54; -.
DR STRING; 81972.D7KY54; -.
DR EnsemblPlants; fgenesh1_pg.C_scaffold_2000558; fgenesh1_pg.C_scaffold_2000558; fgenesh1_pg.C_scaffold_2000558.
DR GeneID; 9324276; -.
DR Gramene; fgenesh1_pg.C_scaffold_2000558; fgenesh1_pg.C_scaffold_2000558; fgenesh1_pg.C_scaffold_2000558.
DR KEGG; aly:9324276; -.
DR eggNOG; KOG0543; Eukaryota.
DR HOGENOM; CLU_013615_13_4_1; -.
DR OrthoDB; 25281at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.40; -; 3.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46512; PEPTIDYLPROLYL ISOMERASE; 1.
DR PANTHER; PTHR46512:SF9; TETRATRICOPEPTIDE REPEAT DOMAIN 9; 1.
DR Pfam; PF00254; FKBP_C; 3.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF54534; FKBP-like; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50059; FKBP_PPIASE; 3.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 65..154
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 182..273
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 301..393
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT REPEAT 492..525
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 584 AA; 64753 MW; C3297E209BCED05B CRC64;
MDSSAIALGA PQITSSDDEE LDEEEGEVIE SAPPLQIGEE RVLGSLHIKK KMLELGTGYE
TPEHDAEVTV HYVGTLLDGT IFYSTRDKSE PVTLTLKVDE VRAPRGLGHC IMTMKKGEIA
LFTLPVDQGY GAEGYDNVPP NSVIQFEIEL FSWIDVVDVR RDGGIIKKII EKGDKNGKPS
DLDEVLVKYQ VELLDSTIVA KSPDQGIQFC VNDGHLCPAL PLAIVSMHPG EKVKLIVQPQ
YGFGEEGRSS SGIINAVPPN SVLNIDVLLV SYKPVIDVVG DSKVFKKILR DGEGSSVADD
GATVTVSYVA KLEDGTIFER KEVGEEEPLV FVTDEEQVIT GLDKAAATMK KGEKAVLKIS
PEYGFGNVEV QRDLAKVPQC STLIYEVEML DFVKEKTPRE MNNEEKIEAA NRKKEEGNLL
YKNQKYQRAA KKYNKAADFI ETGKFEGDEE KQLKALRVSC FLNAAACSLK LKNFRETIIL
CSEVLDIEFQ NVKALYRRAQ SHIEVGDLIS AEMDIKKALE ADPENREVKS LYKTLKFAKA
ESDRRDAKLY ANMFALSKKL KVVAEEEKMA TNIETTEHSN EQSS
//
