ID D7LJ25_ARALL Unreviewed; 435 AA.
AC D7LJ25;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Vesicle-fusing ATPase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ARALYDRAFT_481753 {ECO:0000313|EMBL:EFH57241.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; GL348716; EFH57241.1; -; Genomic_DNA.
DR RefSeq; XP_002880982.1; XM_002880936.1.
DR AlphaFoldDB; D7LJ25; -.
DR STRING; 81972.D7LJ25; -.
DR EnsemblPlants; fgenesh2_kg.4__813__AT2G27600.1; fgenesh2_kg.4__813__AT2G27600.1; fgenesh2_kg.4__813__AT2G27600.1.
DR GeneID; 9315218; -.
DR Gramene; fgenesh2_kg.4__813__AT2G27600.1; fgenesh2_kg.4__813__AT2G27600.1; fgenesh2_kg.4__813__AT2G27600.1.
DR KEGG; aly:9315218; -.
DR eggNOG; KOG0739; Eukaryota.
DR HOGENOM; CLU_000688_21_2_1; -.
DR OrthoDB; 276256at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005771; C:multivesicular body; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007032; P:endosome organization; IEA:EnsemblPlants.
DR GO; GO:0010091; P:trichome branching; IEA:EnsemblPlants.
DR GO; GO:0007033; P:vacuole organization; IEA:EnsemblPlants.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:EnsemblPlants.
DR CDD; cd02678; MIT_VPS4; 1.
DR CDD; cd19521; RecA-like_VPS4; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015415; Spast_Vps4_C.
DR InterPro; IPR045253; VPS4_MIT.
DR PANTHER; PTHR23074; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23074:SF175; PROTEIN SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF09336; Vps4_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00745; MIT; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003651};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003651};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT DOMAIN 2..80
FT /note="MIT"
FT /evidence="ECO:0000259|SMART:SM00745"
FT DOMAIN 164..300
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 73..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 48551 MW; 700E77E074C63CBC CRC64;
MYSNFKEQAI EYVKQAVHED NAGNYNKAFP LYMNALEYFK THLKYEKNPK IREAITQKFT
EYLRRAEEIR AVLDEGGSGP GSNGDAAVAT RPKTKPKDGE GGGKDGEDPE QSKLRSGLNS
AIVREKPNIK WSDVAGLESA KQALQEAVIL PVKFPQFFTG KRRPWRAFLL YGPPGTGKSY
LAKAVATEAD STFFSVSSSD LVSKWMGESE KLVSNLFEMA RESAPSIIFV DEIDSLCGTR
GEGNESEASR RIKTELLVQM QGVGHNDEKV LVLAATNTPY ALDQAIRRRF DKRIYIPLPE
AKARQHMFKV HLGDTPHNLT EPDFEYLGQK TEGFSGSDVS VCVKDVLFEP VRKTQDAMFF
FKSPDGTWMP CGPRHPGAIQ TTMQDLAAKG LAEKIIPPPI TRTDFEKVLA RQKPTVSKSD
LDVHERFTQE FGEEG
//
