ID D7LUY4_ARALL Unreviewed; 631 AA.
AC D7LUY4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=ARALYDRAFT_906899 {ECO:0000313|EMBL:EFH52534.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; GL348717; EFH52534.1; -; Genomic_DNA.
DR RefSeq; XP_002876275.1; XM_002876229.1.
DR AlphaFoldDB; D7LUY4; -.
DR STRING; 81972.D7LUY4; -.
DR EnsemblPlants; scaffold_502603.1; scaffold_502603.1; scaffold_502603.1.
DR GeneID; 9312343; -.
DR Gramene; scaffold_502603.1; scaffold_502603.1; scaffold_502603.1.
DR KEGG; aly:9312343; -.
DR eggNOG; KOG0167; Eukaryota.
DR HOGENOM; CLU_006348_5_1_1; -.
DR OrthoDB; 2721872at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0070696; F:transmembrane receptor protein serine/threonine kinase binding; IEA:EnsemblPlants.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:EnsemblPlants.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF111; U-BOX DOMAIN-CONTAINING PROTEIN 14; 1.
DR Pfam; PF00514; Arm; 3.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 5.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 246..320
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 386..428
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 509..551
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 631 AA; 69226 MW; E67BA9F6A27A938B CRC64;
MGLTNCSHEE LMSRLVDSVK EISGFSSSRG FIGKIQGDLV RRITLLSPFF EELIDVNVEL
KEDQIAGFEV MRIALDSSLE LFRSVHGGSK LFQIFDRDSL VLKFHDMTVE IEAALSQIPY
AKIEVSEEVR EQVQLLHFQF KRAKERREES DLQLSHDLAM AEDVMDPDPN ILKRLSQELQ
LSTIDELKKE SHAIHEYFLS YDGDPDDCFE RMSSLLKKLV DFVTMESSDP DPSTGNRIIS
RHRSPVIPEY FRCPISLELM KDPVIVSTGQ TYERSSIQKW LDAGHKTCPK SQETLLHAGL
TPNYVLKSLI ALWCESNGIE LPQNQGSCRT TKTGGSSSSD CDRTFVVSLL EKLANGTTEQ
QRAAAGELRL LAKRNVDNRV CIAEAGAIPL LVELLSSPDP RTQEHSVTAL LNLSINEGNK
GAIVDAGAIT DIVEVLKNGS MEARENAAAT LFSLSVIDEN KVAIGAAGAI QALISLLEEG
TRRGKKDAAT AIFNLCIYQG NKSRAVKGGI VDPLTRLLKD AGGGMVDEAL AILAILSTNQ
EGKAAIAEAE SIPVLVEIIR TGSPRNRENA AAILWYLCIG NMERLNVARE VGADVALKEL
TENGTDRAKR KAASLLELIQ QTEVVAVSTV P
//
