ID D7M0H5_ARALL Unreviewed; 1180 AA.
AC D7M0H5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ARALYDRAFT_487553 {ECO:0000313|EMBL:EFH47520.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; GL348718; EFH47520.1; -; Genomic_DNA.
DR RefSeq; XP_002871261.1; XM_002871215.1.
DR AlphaFoldDB; D7M0H5; -.
DR STRING; 81972.D7M0H5; -.
DR EnsemblPlants; fgenesh2_kg.6__687__AT5G07280.1; fgenesh2_kg.6__687__AT5G07280.1; fgenesh2_kg.6__687__AT5G07280.1.
DR Gramene; fgenesh2_kg.6__687__AT5G07280.1; fgenesh2_kg.6__687__AT5G07280.1; fgenesh2_kg.6__687__AT5G07280.1.
DR eggNOG; ENOG502QRD1; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0010234; P:anther wall tapetum cell fate specification; IEA:EnsemblPlants.
DR GO; GO:0009556; P:microsporogenesis; IEA:EnsemblPlants.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056:SF58; LEUCINE-RICH REPEAT RECEPTOR PROTEIN KINASE MSP1-LIKE ISOFORM X1; 1.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR Pfam; PF00560; LRR_1; 11.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 15.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1180
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003102592"
FT TRANSMEM 815..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 905..1180
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 934
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1180 AA; 128708 MW; 73BBFBE4E5B94865 CRC64;
MTFLPALFLW FLFFSVSDTA IVDLSSETSS LLSFKLSLEN PSRLSSWNVS SSSSSHCDWV
GVTCLFGRIP KEISTLKNLK ELRLAGNQFS GKIPSEIWKL KQLQTLDLSG NSLTGLLPSQ
LSELHQLLYL DLSDNHFSGS LPPSFFLSFP ALSSLDVSNN SLSGEIPPEI GKLSNLSDLY
MGLNSFSGQI PPEVGNISLL KNFGAPSCFF KGPLPKEISK LKHLAKLDLS YNPLKCSIPK
SFGELQNLSI LNLVSAELIG LIPPELGKCK SLKTLMLSFN SLSGSLPLEL SEIPLLTFSA
ERNQLSGSLP SWIGKWKVLD SLLLANNRFS GEIPREIEDC PMLKHLSLAS NLLTGSIPRE
LCGSGSLEEI DLSGNLLSGT IEEVFNGCSS LVELVLTNNQ INGSIPEDLS KLPLMAVDLD
SNNFTGEIPK SLWKSTNLME FSASYNRLEG YLPAEIGNAA SLTRLVLSDN QLKGEIPREI
GKLTSLSVLN LNSNKLQGKI PKELGDCTCL TTLDLGNNNL QGQIPDRITG LSQLQCLVLS
YNNLSGSIPS KPSAYFHQID MPDLSFLQHH GIFDLSYNRL SGSIPEELGN CVVLVEILLS
NNHLSGEIPA SLSRLTNLTI LDLSGNALTG SIPKEMGHSL KLQGLNLANN QLNGYIPESF
GLLDSLVKLN LTKNKLDGSV PASLGNLKEL THMDLSFNNL SGELSSELST MVKLVGLYIE
QNKFTGEIPS ELGNLTQLEY LDVSENLLSG EIPTKICGLP NLEFLNLAKN NLRGEVPSDG
VCQDPSKALL SGNKELCGRV IGSDCKIDGT KLTHAWGIAG LMLGFTIIVF VFVFSLRRWV
ITKRVKQRDD PERMEESRLK GFVDQNLYFL SGSRSREPLS INIAMFEQPL LKVRLGDIVE
ATDHFSKKNI IGDGGFGTVY KACLPGGKTV AVKKLSEAKT QGNREFMAEM ETLGKVKHPN
LVSLLGYCSF SDEKLLVYEY MVNGSLDHWL RNQTGMLEVL DWSKRLKIAV GAARGLAFLH
HGFIPHIIHR DIKASNILLD GDFEPKVADF GLARLISACE SHVSTVIAGT FGYIPPEYGQ
SARATTKGDV YSFGVILLEL VTGKEPTGPD FKESEGGNLV GWVTQKINQG KAVDVLDPLL
VSVALKNSLL RLLQIAMVCL AETPANRPNM LDVLKALKDI
//
