ID D7M4N5_ARALL Unreviewed; 387 AA.
AC D7M4N5;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN ORFNames=ARALYDRAFT_489451 {ECO:0000313|EMBL:EFH50554.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; GL348718; EFH50554.1; -; Genomic_DNA.
DR RefSeq; XP_002874295.1; XM_002874249.1.
DR AlphaFoldDB; D7M4N5; -.
DR STRING; 81972.D7M4N5; -.
DR EnsemblPlants; fgenesh2_kg.6__2585__AT5G26040.2; fgenesh2_kg.6__2585__AT5G26040.2; fgenesh2_kg.6__2585__AT5G26040.2.
DR Gramene; fgenesh2_kg.6__2585__AT5G26040.2; fgenesh2_kg.6__2585__AT5G26040.2; fgenesh2_kg.6__2585__AT5G26040.2.
DR eggNOG; KOG1344; Eukaryota.
DR HOGENOM; CLU_007727_1_1_1; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR CDD; cd09993; HDAC_classIV; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR044150; HDAC_classIV.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF33; HISTONE DEACETYLASE 11; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..370
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 387 AA; 43714 MW; 2B3B905FD46F4D49 CRC64;
MTDTRVISTW TELTRDSAIY LLFTFFAIKV YIFLFCCTRT SEMSSFSMAT HPEALRRERI
LNSKLYFDVP LSKVSIIYSS AYDISFMGIE KLHPFDSSKW GRVCKFLVSD GFLEEKAIVE
PLEASKIDLL VVHSENYLNS LKSSATVARI TEVPPVAFFP NFLVQQKVLY PFRKQVGGTI
LAAKLATERG WAINIGGGFH HCTAERGGGF CAFADISLCI HFAFLRLRIS RVMIIDLDAH
QGNGHETDLG DDNRVYILDM YNPNIYPFDY RARRFIDQNI EVVSGTTTDE YLRKLDEALE
VASRNFQPEL VIYNAGTDIL DGDPLGLLKI SPDGITSRDE KVFRFAREKS IPLVMLTSGG
YMKSSARVIA DSIENLSRQG LIQTRPE
//
