ID D7M806_ARALL Unreviewed; 168 AA.
AC D7M806;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 56.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060};
GN ORFNames=ARALYDRAFT_349604 {ECO:0000313|EMBL:EFH49341.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. {ECO:0000256|RuleBase:RU364060}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364060}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364060}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 7 family.
CC {ECO:0000256|ARBA:ARBA00009994, ECO:0000256|RuleBase:RU364060}.
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DR EMBL; GL348718; EFH49341.1; -; Genomic_DNA.
DR RefSeq; XP_002873082.1; XM_002873036.1.
DR AlphaFoldDB; D7M806; -.
DR STRING; 81972.D7M806; -.
DR EnsemblPlants; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197.
DR GeneID; 9309150; -.
DR Gramene; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197.
DR KEGG; aly:9309150; -.
DR eggNOG; KOG0570; Eukaryota.
DR HOGENOM; CLU_065214_4_0_1; -.
DR OrthoDB; 11599at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.200; -; 1.
DR InterPro; IPR037212; Med7/Med21-like.
DR InterPro; IPR009244; Mediatior_Med7.
DR InterPro; IPR044888; Mediatior_Med7_sf.
DR PANTHER; PTHR21428; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR PANTHER; PTHR21428:SF11; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR Pfam; PF05983; Med7; 1.
DR SUPFAM; SSF140718; Mediator hinge subcomplex-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364060};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364060};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transcription {ECO:0000256|RuleBase:RU364060};
KW Transcription regulation {ECO:0000256|RuleBase:RU364060}.
FT COILED 137..164
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 168 AA; 19439 MW; 013EDD6BF1420486 CRC64;
MATATYPPPP PYYRLYKDYS ENPNSAPEPP PPIEGTYVCF GGNYTTEDVL PSLEEQGVPQ
LYPKDSNVDY KKELRSLNRE LQLHILELAD VLVDRPSQYA KRIGEISSIF KNLHHLLNSL
RPHQARATLI HIMELQIQRR KQAVEDIKRR REEAQRLLKD AYVTLDGQ
//