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Database: UniProt
Entry: D7M806_ARALL
LinkDB: D7M806_ARALL
Original site: D7M806_ARALL 
ID   D7M806_ARALL            Unreviewed;       168 AA.
AC   D7M806;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   22-FEB-2023, entry version 56.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060};
GN   ORFNames=ARALYDRAFT_349604 {ECO:0000313|EMBL:EFH49341.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. {ECO:0000256|RuleBase:RU364060}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364060}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364060}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 7 family.
CC       {ECO:0000256|ARBA:ARBA00009994, ECO:0000256|RuleBase:RU364060}.
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DR   EMBL; GL348718; EFH49341.1; -; Genomic_DNA.
DR   RefSeq; XP_002873082.1; XM_002873036.1.
DR   AlphaFoldDB; D7M806; -.
DR   STRING; 81972.D7M806; -.
DR   EnsemblPlants; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197.
DR   GeneID; 9309150; -.
DR   Gramene; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197; fgenesh1_pg.C_scaffold_6000197.
DR   KEGG; aly:9309150; -.
DR   eggNOG; KOG0570; Eukaryota.
DR   HOGENOM; CLU_065214_4_0_1; -.
DR   OrthoDB; 11599at2759; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 6.10.140.200; -; 1.
DR   InterPro; IPR037212; Med7/Med21-like.
DR   InterPro; IPR009244; Mediatior_Med7.
DR   InterPro; IPR044888; Mediatior_Med7_sf.
DR   PANTHER; PTHR21428; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR   PANTHER; PTHR21428:SF11; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR   Pfam; PF05983; Med7; 1.
DR   SUPFAM; SSF140718; Mediator hinge subcomplex-like; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364060};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364060};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW   Transcription {ECO:0000256|RuleBase:RU364060};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364060}.
FT   COILED          137..164
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   168 AA;  19439 MW;  013EDD6BF1420486 CRC64;
     MATATYPPPP PYYRLYKDYS ENPNSAPEPP PPIEGTYVCF GGNYTTEDVL PSLEEQGVPQ
     LYPKDSNVDY KKELRSLNRE LQLHILELAD VLVDRPSQYA KRIGEISSIF KNLHHLLNSL
     RPHQARATLI HIMELQIQRR KQAVEDIKRR REEAQRLLKD AYVTLDGQ
//
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