ID D7MA09_ARALL Unreviewed; 540 AA.
AC D7MA09;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Growth-regulating factor {ECO:0000256|RuleBase:RU367127};
GN ORFNames=ARALYDRAFT_656214 {ECO:0000313|EMBL:EFH43192.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- FUNCTION: Transcription activator. {ECO:0000256|RuleBase:RU367127}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU01002, ECO:0000256|RuleBase:RU367127}.
CC -!- DOMAIN: The QLQ domain and WRC domain may be involved in protein-
CC protein interaction and DNA-binding, respectively.
CC {ECO:0000256|RuleBase:RU367127}.
CC -!- SIMILARITY: Belongs to the GRF family. {ECO:0000256|ARBA:ARBA00008122,
CC ECO:0000256|RuleBase:RU367127}.
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DR EMBL; GL348719; EFH43192.1; -; Genomic_DNA.
DR RefSeq; XP_002866933.1; XM_002866887.1.
DR AlphaFoldDB; D7MA09; -.
DR STRING; 81972.D7MA09; -.
DR EnsemblPlants; Al_scaffold_0007_269; Al_scaffold_0007_269; Al_scaffold_0007_269.
DR Gramene; Al_scaffold_0007_269; Al_scaffold_0007_269; Al_scaffold_0007_269.
DR eggNOG; ENOG502QRK7; Eukaryota.
DR HOGENOM; CLU_038207_0_0_1; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:EnsemblPlants.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:EnsemblPlants.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0048364; P:root development; IEA:EnsemblPlants.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR031137; GRF.
DR InterPro; IPR014977; WRC_dom.
DR PANTHER; PTHR31602:SF118; GROWTH-REGULATING FACTOR 2; 1.
DR PANTHER; PTHR31602; GROWTH-REGULATING FACTOR 5; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF08879; WRC; 1.
DR SMART; SM00951; QLQ; 1.
DR PROSITE; PS51666; QLQ; 1.
DR PROSITE; PS51667; WRC; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU367127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU01002}; Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transcription {ECO:0000256|RuleBase:RU367127};
KW Transcription regulation {ECO:0000256|RuleBase:RU367127}.
FT DOMAIN 164..199
FT /note="QLQ"
FT /evidence="ECO:0000259|PROSITE:PS51666"
FT DOMAIN 227..271
FT /note="WRC"
FT /evidence="ECO:0000259|PROSITE:PS51667"
FT REGION 79..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 232..242
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT MOTIF 260..267
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01002"
FT COMPBIAS 79..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 59040 MW; BDBA3AD56CA9D13C CRC64;
MDIGVHVLGS VTSNENESLG LKELRGTKQD RSGFNGEDCL QRSLKLARTT TTKEEEENLS
SSSAAAYCKT MSFQQGIPLM RSASPLSSDS RRQEQMLSFS DKPEALDFSK YVGLDNSSNN
KSSPSPFLHQ IPPPSYFRSS GGYGSGGMMM NMSMQGNFTG VKGPFTLTQW AELEHQALIY
KYITANVPVP SSLLISIKKS FYPYGSLPPS SFGWGTFHLG FAGSNMDPEP GRCRRTDGKK
WRCSRDAVPD QKYCERHINR GRHRSRKPVE VQSGQNQTAA AASKAVATPQ QPVITGNTNR
SNARASSNRS LAIGSQYINP STDSLPNNRG VSIYPSTVSL QPKESPVIQQ KHRNNNNNNN
PFEFGHISSD SLLNPNSAKT YGSSYLDFSS NQDKHSVNHN HNSWPEELKS DWTQLSMSIP
IASSSPSSAH NNNNTGQDTT TLSPLRLSRE LDLSIQTEET TLEPAVKKVN TWIPISWGNS
LGGPLGEVLN STTNSPTLGS SPTGVLQKST FCSLSNNSSV SSPIAENNNR NNGDYFHYTT
//
