ID D7MGC2_ARALL Unreviewed; 551 AA.
AC D7MGC2;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=CRAL-TRIO domain-containing protein {ECO:0000259|PROSITE:PS50191};
GN ORFNames=ARALYDRAFT_912375 {ECO:0000313|EMBL:EFH45150.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004395}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the SFH family. {ECO:0000256|ARBA:ARBA00038020}.
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DR EMBL; GL348719; EFH45150.1; -; Genomic_DNA.
DR RefSeq; XP_002868891.1; XM_002868845.1.
DR AlphaFoldDB; D7MGC2; -.
DR STRING; 81972.D7MGC2; -.
DR EnsemblPlants; scaffold_700117.1; scaffold_700117.1; scaffold_700117.1.
DR GeneID; 9302906; -.
DR Gramene; scaffold_700117.1; scaffold_700117.1; scaffold_700117.1.
DR KEGG; aly:9302906; -.
DR eggNOG; KOG1471; Eukaryota.
DR HOGENOM; CLU_014001_11_1_1; -.
DR OrthoDB; 6048at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.8.20; N-terminal domain of phosphatidylinositol transfer protein sec14p; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR PANTHER; PTHR45657; CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED; 1.
DR PANTHER; PTHR45657:SF19; PHOSPHATIDYLINOSITOL_PHOSPHATIDYLCHOLINE TRANSFER PROTEIN SFH2; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR PRINTS; PR00180; CRETINALDHBP.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 419..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 138..312
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT COILED 472..530
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 551 AA; 63587 MW; 54D890EF78D58878 CRC64;
MADTMVAHLD RHNKIDVEIS EDDNRLTKLC SLKKKAINAT NKFKHSMTKK GRRHSRVACV
SIVDEIDTEE LQAVDAFRQA LILDELLPSK HDDHHMMLRF LRARKFDLEK AKHMWADMLN
WRKEYGADTI MEDFDFKEID EVVQHYPQGY HGVDKEGRPI YIERLGQVDA TKLMKVTTID
RYVKYHVKEF EKTFNVKFPA CSIAAKRHID QSTTILDVQG VGLNNFNKAA KDLLQSIQKI
DNDNYPETLN RMFIINAGYG FRLLWSTVKS FLDPKTTAKI HVLGNKYQTK LLEIIEANEL
PEFLGGKCTC ADKGGCMRSD KGPWNDPEIF KLVQNGEGRC LRRSLSGIEE KTISEYNSET
KKKCEPEETY KQSAAEKEKK FIDKNVDVAD WPTKIHKANN SSTELKDVYS AVNPLERKGY
LYGSVMALLM GIVGVMRLTK NMPRKLTEAN VYSREGSAVY QDGVTVMSRQ EYMVMVKKMT
DLEEKCKSME AQAAFSLERE KILDAALRRV DQLELQLSET NKALDETMTR QHEIMAYIEK
KKKKKRKFLL F
//
