ID D7MIS1_ARALL Unreviewed; 340 AA.
AC D7MIS1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Nucleotide-sugar transporter family protein {ECO:0000313|EMBL:EFH46880.1};
GN ORFNames=ARALYDRAFT_916028 {ECO:0000313|EMBL:EFH46880.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. CMP-
CC Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
CC {ECO:0000256|ARBA:ARBA00006447}.
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DR EMBL; GL348719; EFH46880.1; -; Genomic_DNA.
DR RefSeq; XP_002870621.1; XM_002870575.1.
DR AlphaFoldDB; D7MIS1; -.
DR STRING; 81972.D7MIS1; -.
DR EnsemblPlants; scaffold_703770.1; scaffold_703770.1; scaffold_703770.1.
DR GeneID; 9306692; -.
DR Gramene; scaffold_703770.1; scaffold_703770.1; scaffold_703770.1.
DR KEGG; aly:9306692; -.
DR eggNOG; KOG2234; Eukaryota.
DR HOGENOM; CLU_024645_5_1_1; -.
DR OrthoDB; 200085at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015136; F:sialic acid transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR10231:SF43; UDP-GALACTOSE TRANSLOCATOR; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sugar transport {ECO:0000313|EMBL:EFH46880.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:EFH46880.1}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..340
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003103721"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 340 AA; 38251 MW; FA28BD63ADD91E7C CRC64;
MAATPWYFVA VLLTILTSSQ GILTTLSQSN GGYKYDYATV PFLAEVFKLI VSALFLWREM
RTSSSTTSRI TTDWKSVRLF VIPSLIYLIH NNVQFATLTF VDTSTYQIMG NLKIVTTGIL
FRLFLKRKLS KLQWMAIGLL AVGTTTSQVK GCGEASCDSL FTAPIQGYLL GILSAGLSAL
AGIYTEFLMK RNNDTLYWQN LQLYTFGSLF NVARLIADDF RHGFEKGPWW QRIFDGYSIT
TWMVVLNLGS TGLLVSWLMK YADNIVKVYS TSMAMLLTMV ASIYLFSFKP TLQLFLGIVI
CIMSLHMYFA PPHTLVDLPV TNEAHPKILK QVVVEEKTDS
//
