ID D7MQJ3_ARALL Unreviewed; 1102 AA.
AC D7MQJ3;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ARALYDRAFT_496585 {ECO:0000313|EMBL:EFH41136.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; GL348720; EFH41136.1; -; Genomic_DNA.
DR RefSeq; XP_002864877.1; XM_002864831.1.
DR AlphaFoldDB; D7MQJ3; -.
DR STRING; 81972.D7MQJ3; -.
DR EnsemblPlants; fgenesh2_kg.8__2401__AT5G63930.1; fgenesh2_kg.8__2401__AT5G63930.1; fgenesh2_kg.8__2401__AT5G63930.1.
DR Gramene; fgenesh2_kg.8__2401__AT5G63930.1; fgenesh2_kg.8__2401__AT5G63930.1; fgenesh2_kg.8__2401__AT5G63930.1.
DR eggNOG; ENOG502QPT1; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR OrthoDB; 460883at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF83; RECEPTOR-LIKE PROTEIN KINASE 2; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1102
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003103496"
FT TRANSMEM 738..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 804..1079
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1102 AA; 120485 MW; DCD55809F3CA1FC5 CRC64;
MVKEMMKLAV FFISLLLILL ISETTGLNLE GQYLLDIKSK FVDDMQNLRN WNSNDSVPCG
WTGVMCSNYS SDPEVLSLNL SSMVLSGKLS PSIGGLVHLK QLDLSYNGLS GSIPKEIGNC
SSLEILKLNN NQFDGEIPVE IGKLVSLENL IIYNNRISGS LPVEIGNILS LSQLVTYSNN
ISGQLPRSIG NLKRLTSFRA GQNMISGSLP SEIGGCESLV MLGLAQNQLS GELPKEIGML
KKLSQVILWE NEFSGFIPRE ISNCSSLETL ALYKNQLVGP IPKELGDLQS LEYLYLYRNV
LNGTIPREIG NLSNAIEIDF SENALTGEIP LELGNIEGLE LLHLFENQLT GTIPVELSTL
KNLSKLDLSI NALTGPIPLG FQYLRGLFML QLFQNSLSGT IPPKLGWYSD LWVLDLSDNH
LRGRIPSYLC LHSNMIILNL GTNNLSGNIP TGVTTCKTLV QLRLARNNLV GRFPSNLCKL
VNLTAIELGQ NRFRGSIPRE VGNCSALQRL QLADNDFTGE LPREIGTLSQ LGTLNISSNS
LTGEVPFEIF NCKMLQRLDM CCNNFSGTLP SEVGSLYQLE LLKLSNNNLS GTIPVALGNL
SRLTELQMGG NLFNGSIPRE LGSLTGLQIA LNLSYNKLTG EIPPELSNLV MLEFLLLNNN
NLSGEIPSSF ANLSSLLGYN FSYNSLTGPI PLLRNISISS FIGNEGLCGP PLNQCIQTQP
SAPSQSTVKP GGMRSSKIIA ITAAAIGGVS LMLIALIVYL MRRPVRTVSS SAQDGQQSEM
SLDIYFPPKE GFTFQDLVAA TDNFDESFVV GRGACGTVYK AVLPAGYTLA VKKLASNHEG
GNNNNVDNSF RAEILTLGNI RHRNIVKLHG FCNHQGSNLL LYEYMPKGSL GEILHDPSGN
LDWSKRFKIA LGAAQGLAYL HHDCKPRIFH RDIKSNNILL DDKFEAHVGD FGLAKVIDMP
HSKSMSAIAG SYGYIAPEYA YTMKVTEKSD IYSYGVVLLE LLTGKAPVQP IDQGGDVVNW
VRSYIRRDAL SSGVLDPRLT LEDERIVSHM LTVLKIALLC TSVSPVARPS MRQVVLMLIE
SERSEGEEEH LDTEELTQTT TP
//
