ID   D7MTF6_ARALL            Unreviewed;       660 AA.
AC   D7MTF6;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=ARALYDRAFT_917551 {ECO:0000313|EMBL:EFH40057.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; GL348720; EFH40057.1; -; Genomic_DNA.
DR   RefSeq; XP_002863798.1; XM_002863752.1.
DR   AlphaFoldDB; D7MTF6; -.
DR   STRING; 81972.D7MTF6; -.
DR   EnsemblPlants; scaffold_800951.1; scaffold_800951.1; scaffold_800951.1.
DR   GeneID; 9301614; -.
DR   Gramene; scaffold_800951.1; scaffold_800951.1; scaffold_800951.1.
DR   KEGG; aly:9301614; -.
DR   eggNOG; KOG0167; Eukaryota.
DR   HOGENOM; CLU_006348_5_1_1; -.
DR   OrthoDB; 2721872at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.20.930.20; Adaptor protein Cbl, N-terminal domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR036537; Adaptor_Cbl_N_dom_sf.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR23315:SF49; U-BOX DOMAIN-CONTAINING PROTEIN 15; 1.
DR   Pfam; PF00514; Arm; 2.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00185; ARM; 5.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 3.
DR   PROSITE; PS51698; U_BOX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          289..363
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
FT   REPEAT          421..463
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          462..504
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          503..545
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   660 AA;  73927 MW;  224D619571A5A0EF CRC64;
     MVIVMDADEE STGDAENLEE EVTAEEPIHD EAVDAVEIHD EEVKNGDDDC DGLVSDIVSV
     IEFLDQINGY RKTQQKECFN LVRRLKILIP FLEEIRGFDS PSCRHFVNRL RKVILVAKKL
     LETCSNGSKI YMALDSETMM TRFHSIYEKL NRVLVKTPFD ELTISEDVKE EIDALCKQLK
     KAKRRTDTQD IELAVDMMVV FSKTDPRNAD SAIIERLAKK LELQTTEDLK TETIAIKSLI
     QEKGGLNIET KQHIIELLNK FKKLQGLEAT DILYQPVINK AFTKSTSLIL PHEFLCPITL
     EIMLDPVIIA TGQTYEKESI QKWFDAGHKT CPKTRQELDH LSLAPNYALK NLIMQWCEKN
     NFKIPEKEAS PHSENEQKDE VSLLVEALSS SHLEEQRRSV KQMRLLAREN PENRVLIANA
     GAIPLLVQLL SYPDSGIQEN AVTTLLNLSI DEVNKKLISN EGAIPNIIEI LQNGNREARE
     NSAAALFSLS MLDENKVTIG LSNGIPPLVD LLQHGTLRGK KDALTALFNL SLNSANKGRA
     IDAGIVQPLL NLLKDRNLGM IDEALSILLL LASHPEGRQA IGQLSFIETL VEFIRQGTPK
     NKECATSVLL ELGSNNSSFI LAALQFGVYE YLVEITTSGT NRAQRKANAL IQLISKSEQI
//