ID D7N6M0_9FIRM Unreviewed; 2878 AA.
AC D7N6M0;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Helicase C-terminal domain protein {ECO:0000313|EMBL:EFI42533.1};
GN ORFNames=HMPREF0629_01187 {ECO:0000313|EMBL:EFI42533.1};
OS Peptoniphilus sp. oral taxon 386 str. F0131.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Peptoniphilus.
OX NCBI_TaxID=575609 {ECO:0000313|EMBL:EFI42533.1, ECO:0000313|Proteomes:UP000004712};
RN [1] {ECO:0000313|EMBL:EFI42533.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0131 {ECO:0000313|EMBL:EFI42533.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Izard J., Baranova O.V., Blanton J.M., Tanner A.C., Dewhirst F.E., Haas B.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Peptoniphilus sp. oral taxon 386 strain F0131.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349422; EFI42533.1; -; Genomic_DNA.
DR STRING; 575609.HMPREF0629_01187; -.
DR eggNOG; COG0553; Bacteria.
DR eggNOG; COG0827; Bacteria.
DR eggNOG; COG4646; Bacteria.
DR HOGENOM; CLU_000181_1_1_9; -.
DR Proteomes; UP000004712; Miscellaneous, Scaffold supercont1.1.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:EFI42533.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:EFI42533.1};
KW Hydrolase {ECO:0000313|EMBL:EFI42533.1};
KW Nucleotide-binding {ECO:0000313|EMBL:EFI42533.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004712}.
FT DOMAIN 2274..2442
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 210..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2831..2878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2604..2652
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 213..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2831..2847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2861..2878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2878 AA; 330603 MW; FF1CB09956039B55 CRC64;
MRGQKGIPIL EDYGTYKKVD YIFDVSQTVS RNRDVNEVNL WKFDKEAHQD VLKEMIANEG
YEESESNLEN IFSLSRIYGD EKIGSLMNEL RITDEDRISF VKFVRDSISY AVASRFKVDY
PVDYELLREN ISRLDTISLM SVGETVSDIS GNIIDTTIQK SKELELQKGV LRNREAGYNK
IREEIEKGEN HVLRRDDKER ISETERVFRN GEYGGDSSQN QGEYTKQLGG TDGIHQGISE
SDLRSDEAGL SFTERGAEPL RDVSGSIQGE EADRTPDGYS ETGDSIYEDR EAEADEVLED
RGREQSTVWG DDFSLEGNDH QGNRGNLKEN TEVEIREADK ASFSLPENSY GQIRLSIPLA
QKDIDTVLIN GGNHDGGRLP IIAEFSKGKS NEELGEYLKN TFQGGNGYII DGNEISAWYS
DKGLHFASGT SAREDDTQVL SWSDAANRIA ELLENGEFAT NVEISEAFDY ERDRISESLW
YLIHDLSEEG KEQGFFEFLE KGGGFPDETK RLSEALKNPE YLVDVIKEYG RFLEAYREDR
DVLRFDYHKV DSLYQKLQEL ALPRKEYTSN LTELPKVKAF ITEDEVLATL SMGSGADRGK
ERITEFFKEN HTLQEKADFL KDEYGTGGRS HAVSGLTGSG EWHDAKGIKL EKNDCNDVFL
TWSRVAKHID EILSKNLYLE EKKIESKAER EEAKELQYYS KDEPENLMTD EMIERVPELY
AQEDVELADK EVHAAYIIPF RSNWTWYMTE YDRESGDAFG LVLGIEPEWG YFNLNELKEL
NAQRLVLEDF PKTFQEIKDT ELVKQMSEEE IDRVFNGQLS SKDNQKEQDI FYLSDEMGIS
LEESEGIIDD RSRLSGVSTE DTDNKDNLLD EKSPVQSTLF DYIQQKEEVE LNEKEESLAE
QFAVKQGDTV YFDHEAYIAR DIEKNKVNGK PEVWLYPARD GNRQIAIVPF MDNEELLKKI
SLERPNFLVG DEVRYKDKDC TITRFDNMGN NLKTVTVMDN TEYLGGMITG SDVIPYRLES
DLERIFENLT YTKAKDTIQD IDEKAEKPKI EAHNFKIIEE ILPEKLTPSE RLNQNLEAIS
MLKRVESGQR ELDNTAQEVL VKYVGWGGLS EVFDEERGGQ WKKARSFLKE NLSQAEYEAA
RESTLTSFYT PKTVIDSIYS TLSGMEFKNG NILEPSMGIG NFIGNLPDEM KKSKFYGVEL
DSVSGRIGKL LYPESDIQIK GLEETSFSNN FFDVVIGNVP FGEYKVNDRE YNKNNFLIHD
YFFAKSIDKV RNGGIIAFIT SSGTMDKKDE SVRRYLAARA GFLGAIRLPN DTFKGVAGTE
VTSDIIFLKK RDSIRERDED WIHLSEDEKG LTYNKYFVEN PQMVLGSMEE VSGKFGNTLA
CLPRENADLK ELLARASEEI SKGATYEEIE LLEDEISTMP ATDDVKNFSY TIIDDEVYYR
ENSLFVKKEI TEKNKEKIKD YLELNTALKD VIYKQKEDFS DDEVKKSQEK LNEVYDGFSK
KHGFVNNLSN TRALKEDSNF PLVSSIEILD EEENFKEKGD IFSKRTITKA KTIDHVDTSL
EALVLSMSEK GYVDFDYMES LTGKDRPTLI EELRGEIYLN IREEQNFYRP LSFNPEDGDL
PFACASGSDS YKYGYVTKDE YLSGNIRDKI AIVDSYLSKL RQTERELPHL GYAEDGKEKE
LISYEMNRLE YQKAELTKVL PKALEASEIS VRLGATWIPM KDIEKFIFET LKTPGYAKWD
IKVKFSNLTS EWNVEGKSAD RGNDLAEMTY GTSRVNAYKL IEDALNLKET KVFDQIENPD
GSKSSVLNKK ETLLAGQKQE LLKEEFKNWI FSDQERRNRL VKLYNERFNS IRNREYDGSN
LSFEGMNTEI ELRPHQRNAI ARSLYGGNTL LAHVVGSGKT FEMVASAMES KRLGMCSKSL
FVVPNHLTGQ IGREFMQLYP SANIMVADKK DFEPKNRKRF IGKIATGEYD AVVIGHTQFE
KIPMSKEYQE KHIQDQIDEI LNYIEEYKHD RNQNFTVKQL EKTKKKLEAR LEKLNDDFKK
DDVITFEELG VDKLFVDEAH GFKNLYLHTK MRNVAGIGQS EAFKSSDMFM KCRYMDEMTN
GKGIVFATGT PVSNSMTELY TMQRYLQYEN LKKNHLEHFD AWASTFGETQ SAFELAPEGT
GYRVKTRFSK FYNLPELMSM FKEVADIQTA DTLDLPTPEA HYEVIKTLPS EEQKEILKGL
SERADKVRNR VVEPDEDNML KITNDGKKLA LDQRLLNPLL PDNSDSKVNV CVKNVFAIWD
KTKDDRSTQL LFSDMSTPKG DGEFNIYDDI REKLVAMGIP KEEIAFIHEA NSDKQKDELF
AKVRKGDVRI LLGSTQKMGA GTNVQNKLIA LHDLDVPWRP ADLEQRAGRI VRQGNENKEV
NIYRYVTENT FDAYLWQTIE NKQKFISQIM TSKTPVRVAE DVDESSLNYA EIKALATGDP
KIKEKMDLDN EVTKLKMLEA NYKSNRYRLE DKVAKNYPEE ITRTEKLIEA VKNDISEVEP
KAEGEEKFTS ITILGEKITD KKLAGEKLLE AISKIKINES KMIGKYRNMD LEVSYNFFTN
EHNFSLNGAA KHSGELGTSA DGNITRLDNA LEKMPEKLKR LEEKLISTKE QLENAKEELK
KPFEKADELK TKVLRLAELN KLLDMGEVEE KRNDNPLVED VKRAIIDFCN REYEENHSYD
EFDTLYPDLK HIGIAYTDTP DERHGIQYEL NLEDYTWTQY IDDTPIKTES FDYENKGENE
ALKNMKNEIE LSSFEDLVYV DSEDLRAATG LDIDDEGNFY DPLAKDLDND GIPDRYDNDF
RDSDYFESTY DVEDNLHTKE ETAQRTDDKP SILGQIRAYQ SESKTEEKQT TKEQEYAR
//
