ID D7SRV4_VITVI Unreviewed; 394 AA.
AC D7SRV4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Squalene cyclase C-terminal domain-containing protein {ECO:0000259|Pfam:PF13243};
GN OrderedLocusNames=VIT_09s0054g01470 {ECO:0000313|EMBL:CBI18386.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI18386.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
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DR EMBL; FN594972; CBI18386.3; -; Genomic_DNA.
DR AlphaFoldDB; D7SRV4; -.
DR STRING; 29760.D7SRV4; -.
DR PaxDb; 29760-VIT_09s0054g01470-t01; -.
DR eggNOG; KOG0497; Eukaryota.
DR HOGENOM; CLU_009074_0_0_1; -.
DR InParanoid; D7SRV4; -.
DR OMA; TEEVENC; -.
DR Proteomes; UP000009183; Chromosome 9.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IBA:GO_Central.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IBA:GO_Central.
DR Gene3D; 1.50.10.20; -; 1.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 42..375
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 394 AA; 44352 MW; 639B2CCDC5C2E959 CRC64;
MLTCWVEDPN GDYFKKHLAR IKDFIWVAED GIKMQTFGSQ EWDTGFALQA LLACNMTNEI
GPTLKKGHEF IKESQVKDNP SGDFKSMYRH ISKGSWTFSD QDHGWQVSDC TAEGLKCCLL
FSMMAPEIVG MTMEPERLFD SVNILLSLQS KNGGLAVWEP AGASEWLELL NPSEIFEDIV
IEHEYVECTA SAIQALVLFK KLYPQHRTKE IDNFITNATK YIEDQQMPDG SWYGNWGVCF
TYGSWFALGG LAAASRTYHN CLAIGRAVEF LLKSQGDDGG WGESYISCQD KNLTPLEGNK
SNLVQTGWAL MGLLSSGQAE RDPTPLHRAA KLLINSQMED GDFPQQEITG AFMKNCMLHY
ADYRNIFPLW ALAEYVSECH RLKSGCIAMP KKHL
//
